Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GAPDH | P04406 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16559839 | 0.95 | ELANE (0.40) | BACE1ELANEKMT2AATMGAA | |
| SCHEMBL18308842 | 0.91 | BACE1 (0.39) | BACE1ELANEKMT2AATMGAA | |
| SCHEMBL16559833 | 0.86 | TDP1 (0.40) | BACE1ELANEKMT2AATMGAA | |
| SCHEMBL16559832 | 0.86 | TDP1 (0.38) | BACE1ELANEKMT2AATMGAA | |
| SCHEMBL19158258 | 0.86 | KMT2A (0.37) | BACE1ELANEKMT2AATMPDGFRB | |
| SCHEMBL17794408 | 0.85 | BACE1 (0.39) | BACE1ELANEKMT2AATMGAA | |
| SCHEMBL16573121 | 0.84 | ELANE (0.39) | BACE1ELANEKMT2AATMTDP1 | |
| SCHEMBL19158864 | 0.84 | ELANE (0.40) | ELANEKMT2AATMPDGFRBPDGFRA | |
| SCHEMBL22459581 | 0.83 | BACE1 (0.43) | BACE1ELANEKMT2AATMMAPT | |
| SCHEMBL21101841 | 0.83 | ELANE (0.50) | BACE1ELANEKMT2AATMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2848676-B1 | Liquid crystal medium | MERCK PATENT GMBH (DE) | 2017-07-26 | — | — | EP | disclosed |