Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 19/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19649516 | 0.87 | PTPRB (0.68) | PTPRB | |
| SCHEMBL22627135 | 0.86 | PTPRB (0.64) | PTPRB | |
| SCHEMBL16573545 | 0.86 | PTPRB (0.64) | PTPRB | |
| SCHEMBL12084628 | 0.81 | PTPRB (0.72) | PTPRB | |
| SCHEMBL16573550 | 0.81 | PTPRB (0.58) | PTPRB | |
| SCHEMBL14652301 | 0.81 | PTPRB (0.69) | PTPRB | |
| SCHEMBL468155 | 0.80 | PTPRB (1.00) | PTPRB | |
| SCHEMBL468153 | 0.80 | PTPRB (1.00) | PTPRB | |
| SCHEMBL14305275 | 0.80 | PTPRB (0.70) | PTPRB | |
| SCHEMBL468188 | 0.79 | PTPRB (0.78) | PTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038265-B1 | Human protein-tyrosine phosphatase inhibitors and methods of use | AERPIO THERAPEUTICS INC (US) | 2015-03-18 | — | — | EP | disclosed |