Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 20/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16573542 | 0.81 | PTPRB (0.67) | PTPRB | |
| SCHEMBL16573545 | 0.81 | PTPRB (0.64) | PTPRB | |
| SCHEMBL22627135 | 0.81 | PTPRB (0.64) | PTPRB | |
| SCHEMBL3547545 | 0.81 | PTPRB (0.56) | PTPRB | |
| SCHEMBL3547542 | 0.81 | PTPRB (0.56) | PTPRB | |
| SCHEMBL500546 | 0.79 | PTPRB (0.68) | PTPRB | |
| SCHEMBL500545 | 0.79 | PTPRB (0.68) | PTPRB | |
| SCHEMBL679203 | 0.78 | PTPRB (0.53) | PTPRB | |
| SCHEMBL679204 | 0.78 | PTPRB (0.53) | PTPRB | |
| SCHEMBL23377826 | 0.77 | PTPRB (0.72) | PTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038265-B1 | Human protein-tyrosine phosphatase inhibitors and methods of use | AERPIO THERAPEUTICS INC (US) | 2015-03-18 | — | — | EP | disclosed |