SCHEMBL16576286

SCHEMBL16576286

CSCC[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)OC(C)(C)C)C(=O)NN

nearest known ligand 0.64

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
REN P00797 7/20 0.64
BACE1 P56817 10/20 0.55
BACE2 Q9Y5Z0 1/20 0.54
CCKBR P32239 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2507078 0.92 REN (0.65) RENBACE1BACE2
SCHEMBL2507079 0.92 REN (0.65) RENBACE1BACE2
SCHEMBL20825230 0.90 REN (0.66) RENCCKBR
SCHEMBL21467154 0.88 REN (0.64) RENBACE1BACE2
SCHEMBL19559785 0.88 REN (0.67) RENCCKBR
SCHEMBL16576297 0.88 REN (0.61) RENBACE1BACE2CCKBR
SCHEMBL19547922 0.87 REN (0.49) REN
SCHEMBL19547920 0.87 REN (0.49) REN
SCHEMBL18085011 0.86 REN (0.62) RENCCKBR
SCHEMBL17951662 0.86 REN (0.66) RENBACE1BACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9850275-B2 Photolabile linker for the solid-phase synthesis of hydrazides and pyranopyrazoles DANMARKS TEKNISKE UNIVERSITET (DK) 2017-12-26 US disclosed
US-9850275-B2 Photolabile linker for the solid-phase synthesis of hydrazides and pyranopyrazoles DANMARKS TEKNISKE UNIVERSITET (DK) 2017-12-26 US disclosed
EP-3044204-B1 A PHOTOLABILE LINKER FOR THE SOLID-PHASE SYNTHESIS OF HYDRAZIDES AND PYRANOPYRAZOLES UNIV DANMARKS TEKNISKE (DK) 2017-11-08 EP disclosed
US-20160272672-A1 PHOTOLABILE LINKER FOR THE SOLID-PHASE SYNTHESIS OF HYDRAZIDES AND PYRANOPYRAZOLES DANMARKS TEKNISKE UNIVERSITET (DK) 2016-09-22 US disclosed
US-20160272672-A1 PHOTOLABILE LINKER FOR THE SOLID-PHASE SYNTHESIS OF HYDRAZIDES AND PYRANOPYRAZOLES DANMARKS TEKNISKE UNIVERSITET (DK) 2016-09-22 US disclosed
WO-2015036481-A1 A PHOTOLABILE LINKER FOR THE SOLID-PHASE SYNTHESIS OF HYDRAZIDES AND PYRANOPYRAZOLES DANMARKS TEKNISKE UNIVERSITET (DK) 2015-03-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160272672-A1 PHOTOLABILE LINKER FOR THE SOLID-PHASE SYNTHESIS OF HYDRAZIDES AND PYRANOPYRAZOLES VIP, PTMS, SPPL2B REN 2192/4885BACE1 494/4885BACE2 1960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.