⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12258453 | 0.80 | NPSR1 (0.35) | — | |
| SCHEMBL17811629 | 0.70 | CNR1 (0.30) | — | |
| SCHEMBL12125884 | 0.70 | BCHE (0.31) | — | |
| SCHEMBL16577352 | 0.62 | PDE10A (0.36) | — | |
| SCHEMBL18703514 | 0.60 | GRM5 (0.30) | — | |
| SCHEMBL12040242 | 0.60 | PDK2 (0.42) | — | |
| SCHEMBL2326043 | 0.59 | BCHE (0.32) | — | |
| SCHEMBL13444940 | 0.57 | USP2 (0.31) | — | |
| SCHEMBL20562001 | 0.56 | PTGS1 (0.32) | — | |
| SCHEMBL15428150 | 0.55 | ACHE (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309231-B2 | Bridged ring compounds as hepatitis C virus (HCV) inhibitors and pharmaceutical applications thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-04-12 | — | — | US | disclosed |
| US-20150079028-A1 | Bridged Ring compounds As Hepatitis C Virus (HCV) Inhibitors And Pharmaceutical Applications Thereof | SUNSHINE LAKE PHARMA CO., LTD (CN) | 2015-03-19 | — | — | US | disclosed |