SCHEMBL16578024

SCHEMBL16578024

CCC(C)(C)OC(=O)c1ccc(C(=O)Oc2ccc(C(C)(CC)c3ccc(OC(C)(C)C)cc3)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.45
TDP1 Q9NUW8 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
PRSS1 P07477 4/20 0.41
ACR P10323 4/20 0.41
KMT2A Q03164 4/20 0.38
MEN1 O00255 3/20 0.38
ELANE P08246 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ALDH1A1 P00352 1/20 0.37
THRB P10828 1/20 0.37
EPHX2 P34913 1/20 0.35
NR1H4 Q96RI1 1/20 0.35
HSD17B10 Q99714 1/20 0.35
PARP10 Q53GL7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12352685 0.94 MAPT (0.46) MAPTTDP1L3MBTL1PRSS1ACR
SCHEMBL14817453 0.89 MAPT (0.42) MAPTTDP1L3MBTL1PRSS1ACR
SCHEMBL16626807 0.85 EPHX2 (0.39) MAPTTDP1L3MBTL1PRSS1ACR
SCHEMBL12352686 0.84 MAPT (0.42) MAPTTDP1L3MBTL1PRSS1ACR
SCHEMBL14817445 0.81 MAPT (0.39) MAPTTDP1L3MBTL1PRSS1ACR
SCHEMBL12352797 0.80 ELANE (0.48) MAPTTDP1L3MBTL1PRSS1ACR
SCHEMBL28656541 0.77 ELANE (0.49) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL18557679 0.76 CYP1A2 (0.42) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL141556 0.76 CA1 (0.58) MAPTTDP1L3MBTL1PRSS1ACR
SCHEMBL7185797 0.76 NPC1 (0.40) MAPTSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9442400-B2 Electrophotographic photoreceptor including a copolymer polyarylate resin, production method therefor, electrophotographic device including the photoreceptor, and production method for the copolymer polyarylate resin FUJI ELECTRIC CO., LTD. (JP) 2016-09-13 US disclosed
US-20150079510-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PRODUCTION METHOD THEREFOR, ELECTROPHOTOGRAPHIC DEVICE, AND PRODUCTION METHOD FOR COPOLYMER POLYARYLATE RESIN FUJI ELECTRIC CO., LTD. (JP) 2015-03-19 US disclosed