Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18557679 | 0.90 | CYP1A2 (0.42) | EPHX2NR1H4ELANETRPV1TDP1 | |
| SCHEMBL19217953 | 0.89 | CA12 (0.40) | EPHX2NR1H4ELANETRPV1TDP1 | |
| SCHEMBL16578024 | 0.85 | MAPT (0.45) | EPHX2NR1H4ELANETDP1MAPT | |
| SCHEMBL12352797 | 0.82 | ELANE (0.48) | EPHX2NR1H4ELANETDP1MAPT | |
| SCHEMBL5366422 | 0.81 | CYP1A2 (0.49) | ELANETDP1MAPTCYP1A2CYP2D6 | |
| SCHEMBL11888430 | 0.80 | CA1 (0.48) | EPHX2NR1H4TDP1MAPTL3MBTL1 | |
| SCHEMBL24973109 | 0.80 | MEN1 (0.39) | MAPTCYP1A2ALDH1A1HSD17B10PPARG | |
| SCHEMBL12085817 | 0.79 | TRPV1 (0.38) | EPHX2NR1H4ELANETRPV1TDP1 | |
| SCHEMBL12352685 | 0.79 | MAPT (0.46) | EPHX2NR1H4ELANETDP1MAPT | |
| SCHEMBL12832692 | 0.79 | ELANE (0.59) | ELANETDP1MAPTHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051128-A1 | POLYDIORGANOSILOXANE-POLYCARBONATE BLOCK COPOLYMERS | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2015-04-09 | — | — | WO | disclosed |