Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 3/20 | 0.45 |
| ▸ | CCND1 | P24385 | 3/20 | 0.45 |
| ▸ | CCND2 | P30279 | 3/20 | 0.45 |
| ▸ | CCND3 | P30281 | 3/20 | 0.45 |
| ▸ | JAK2 | O60674 | 7/20 | 0.44 |
| ▸ | BRD4 | O60885 | 7/20 | 0.44 |
| ▸ | JAK1 | P23458 | 4/20 | 0.43 |
| ▸ | BRD2 | P25440 | 4/20 | 0.43 |
| ▸ | JAK3 | P52333 | 4/20 | 0.43 |
| ▸ | BRD3 | Q15059 | 4/20 | 0.43 |
| ▸ | BRDT | Q58F21 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16580711 | 0.91 | JAK2 (0.53) | WEE1HTR6CDK4CCND1CCND3 | |
| SCHEMBL16580982 | 0.91 | WEE1 (0.46) | WEE1CDK4CCND1CCND2CCND3 | |
| SCHEMBL16580744 | 0.89 | MAPT (0.46) | CDK4CCND1CCND2CCND3JAK2 | |
| SCHEMBL16570057 | 0.88 | JAK2 (0.49) | WEE1KCNH2HTR6JAK2BRD4 | |
| SCHEMBL16570263 | 0.87 | JAK2 (0.49) | CDK4CCND1CCND2CCND3JAK2 | |
| SCHEMBL16570581 | 0.86 | HTR6 (0.46) | WEE1KCNH2HTR6JAK2JAK3 | |
| SCHEMBL16570820 | 0.80 | WEE1 (0.47) | WEE1CDK4CCND1JAK2BRD4 | |
| SCHEMBL16570822 | 0.80 | WEE1 (0.47) | WEE1CDK4CCND1JAK2BRD4 | |
| SCHEMBL16580846 | 0.80 | WEE1 (0.47) | WEE1CDK4CCND1JAK2BRD4 | |
| SCHEMBL16570146 | 0.78 | JAK2 (0.58) | WEE1CDK4CCND1CCND3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160222014-A1 | COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS | ASANA BIOSCIENCES, LLC (US) | 2016-08-04 | — | — | US | claimed |
| US-20160222014-A1 | COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS | ASANA BIOSCIENCES, LLC (US) | 2016-08-04 | — | — | US | disclosed |
| WO-2015038417-A1 | COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS | ASANA BIOSCIENCES, LLC (US) | 2015-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160222014-A1 | COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS | SRC, PTK2, FYN | WEE1 1512/4885KCNH2 4357/4885HTR6 1484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.