Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 3/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.32 |
| ▸ | RORB | Q92753 | 1/20 | 0.32 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16581290 | 0.98 | TNKS (0.34) | EGFRTNKSTNKS2ADORA2AADORA1 | |
| SCHEMBL16581160 | 0.89 | ADORA2A (0.35) | TNKSTNKS2ADORA2AADORA1ADORA2B | |
| SCHEMBL19784902 | 0.89 | EGFR (0.36) | EGFRTNKSTNKS2LIMK1MEN1 | |
| SCHEMBL16581302 | 0.87 | EGFR (0.34) | EGFRTNKSTNKS2LIMK1ALDH1A1 | |
| SCHEMBL16905962 | 0.85 | NR1I3 (0.45) | ADORA2AADORA1ADORA2BLIMK1RORB | |
| SCHEMBL17565579 | 0.85 | EGFR (0.44) | EGFRTNKSTNKS2LIMK1RORB | |
| SCHEMBL16581111 | 0.85 | ESR1 (0.36) | TNKSTNKS2ADORA2AADORA1ADORA2B | |
| SCHEMBL23327840 | 0.83 | EGFR (0.42) | EGFRTNKSTNKS2LIMK1RORB | |
| SCHEMBL16905798 | 0.83 | NR1I3 (0.43) | TNKSTNKS2ADORA2AADORA1ADORA2B | |
| SCHEMBL16581156 | 0.83 | CYP11B1 (0.35) | TNKSTNKS2ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015037675-A1 | BENZOTHIENOPYRIMIDINE COMPOUND, METHOD FOR PRODUCING SAME AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING SAME | 東ソー株式会社 (JP) | 2015-03-19 | — | — | WO | disclosed |