SCHEMBL17565579

SCHEMBL17565579

Brc1cccc(-c2nc(-c3ccccc3)c3sc4ccccc4c3n2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ EGFR P00533 1/20 0.44
▸ RAB9A P51151 3/20 0.41
▸ NPC1 O15118 2/20 0.41
▸ TSHR P16473 2/20 0.41
▸ SMN1; SMN2 Q16637 2/20 0.41
▸ ALDH1A1 P00352 2/20 0.41
▸ MAPT P10636 2/20 0.41
▸ HPGD P15428 2/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ HTT P42858 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ ABCG2 Q9UNQ0 3/20 0.39
▸ ABCB1 P08183 1/20 0.39
▸ MAOA P21397 1/20 0.37
▸ MAOB P27338 1/20 0.37
▸ AURKA O14965 1/20 0.37
▸ RORB Q92753 1/20 0.37
▸ MYC P01106 1/20 0.36
▸ WDR5 P61964 1/20 0.36
▸ TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23327840 0.97 EGFR (0.42) EGFRRAB9ANPC1TSHRSMN1; SMN2
SCHEMBL23327849 0.95 EGFR (0.41) EGFRRAB9ANPC1TSHRSMN1; SMN2
SCHEMBL30536855 0.95 EGFR (0.44) EGFRRAB9ANPC1TSHRSMN1; SMN2
SCHEMBL31683825 0.93 EGFR (0.41) EGFRRAB9ANPC1TSHRSMN1; SMN2
SCHEMBL18158883 0.93 EGFR (0.42) EGFRRAB9ANPC1TSHRSMN1; SMN2
SCHEMBL18017741 0.91 TNKS (0.39) EGFRALDH1A1MAPTMEN1KMT2A
SCHEMBL18017652 0.89 TNKS (0.38) MAPTMEN1KMT2ATNKSTNKS2
SCHEMBL18017743 0.89 TNKS (0.38) MAPTMEN1KMT2ATNKSTNKS2
SCHEMBL18017661 0.89 TNKS (0.38) MAPTMEN1KMT2ATNKSTNKS2
SCHEMBL31683838 0.89 LIMK1 (0.38) EGFRRAB9ANPC1SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230320211-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT-EMITTING DEVICE LT MATERIALS CO., LTD. (KR) 2023-10-05 — — US disclosed
US-20230320211-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT-EMITTING DEVICE LT MATERIALS CO., LTD. (KR) 2023-10-05 — — US disclosed
US-11706983-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-18 — — US disclosed
WO-2021230651-A1 ORGANIC ELECTRONIC ELEMENT COMPRISING COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2021-11-18 — — WO disclosed
US-9780312-B2 Carbazole-based compound and organic light emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-10-03 — — US disclosed
US-9780312-B2 Carbazole-based compound and organic light emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-10-03 — — US disclosed
EP-2991128-B1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2017-04-12 — — EP disclosed
US-20160111657-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-04-21 — — US disclosed
US-20160111657-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-04-21 — — US disclosed
US-20160072078-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-03-10 — — US disclosed
US-20160072078-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-03-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230320211-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT-EMITTING DEVICE ORC3, CRY1, SUN2 EGFR 3898/4885RAB9A 3732/4885NPC1 2890/4885
US-20160111657-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME CRY1, CYP1A1, CYP1B1 EGFR 3927/4885RAB9A 2401/4885NPC1 2692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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