Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18064646 | 0.91 | RORC (1.00) | RORC | |
| SCHEMBL16582393 | 0.84 | RORC (1.00) | RORC | |
| SCHEMBL16582389 | 0.84 | RORC (1.00) | RORC | |
| SCHEMBL16582388 | 0.84 | RORC (1.00) | RORC | |
| SCHEMBL18064653 | 0.84 | RORC (1.00) | RORC | |
| SCHEMBL18064651 | 0.83 | RORC (1.00) | RORC | |
| SCHEMBL18086803 | 0.79 | RORC (0.86) | RORC | |
| SCHEMBL18064618 | 0.78 | RORC (1.00) | RORC | |
| SCHEMBL16569340 | 0.77 | RORC (1.00) | RORC | |
| SCHEMBL18064637 | 0.76 | RORC (1.00) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015036411-A1 | KETO-IMIDAZOPYRIDINE DERIVATIVES AS RORc MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2015-03-19 | — | — | WO | disclosed |