Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.52 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.47 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 2/20 | 0.45 |
| ▸ | RXRB | P28702 | 2/20 | 0.45 |
| ▸ | RXRG | P48443 | 2/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4412749 | 0.83 | PTGS1 (0.60) | KIF11PTGS1TAAR1MKNK1MKNK2 | |
| SCHEMBL26784179 | 0.82 | ABL1 (0.49) | KIF11RXRARXRBRXRGERN1 | |
| SCHEMBL16603396 | 0.81 | CYP17A1 (0.53) | CYP17A1CYP11B1CYP21A2RXRARXRB | |
| SCHEMBL26037182 | 0.81 | TAAR1 (0.69) | KIF11CYP17A1CYP11B1TAAR1MKNK1 | |
| SCHEMBL15725297 | 0.80 | KIF11 (0.59) | KIF11CYP17A1CYP11B1PTGS1RXRA | |
| SCHEMBL14152972 | 0.80 | KIF11 (0.59) | KIF11CYP17A1CYP11B1PTGS1RXRA | |
| SCHEMBL12562821 | 0.80 | SLC6A4 (0.45) | CYP17A1CYP11B1CYP21A2RXRARXRB | |
| SCHEMBL679970 | 0.80 | MKNK1 (0.56) | KIF11PTGS1MKNK1MKNK2PDK2 | |
| SCHEMBL11310791 | 0.80 | MKNK1 (0.56) | KIF11PTGS1MKNK1MKNK2PDK2 | |
| SCHEMBL25365121 | 0.78 | MKNK1 (0.53) | KIF11CYP17A1CYP11B1CYP21A2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181484-B2 | Compound having 2-fluorophenyloxymethane structure | DIC CORPORATION (JP) | 2015-11-10 | — | — | US | disclosed |
| US-9181484-B2 | Compound having 2-fluorophenyloxymethane structure | DIC CORPORATION (JP) | 2015-11-10 | — | — | US | disclosed |
| US-9181484-B2 | Compound having 2-fluorophenyloxymethane structure | DIC CORPORATION (JP) | 2015-11-10 | — | — | US | disclosed |
| US-20150087847-A1 | COMPOUND HAVING 2-FLUOROPHENYLOXYMETHANE STRUCTURE | DIC CORPORATION (JP) | 2015-03-26 | — | — | US | disclosed |
| US-20150087847-A1 | COMPOUND HAVING 2-FLUOROPHENYLOXYMETHANE STRUCTURE | DIC CORPORATION (JP) | 2015-03-26 | — | — | US | disclosed |
| US-20150087847-A1 | COMPOUND HAVING 2-FLUOROPHENYLOXYMETHANE STRUCTURE | DIC CORPORATION (JP) | 2015-03-26 | — | — | US | disclosed |