SCHEMBL16585358

SCHEMBL16585358

ClCCc1cnc2ccccc2n1

nearest known ligand 0.77

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 18/20 0.77
MEN1 O00255 1/20 0.55
MAPT P10636 1/20 0.55
KMT2A Q03164 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12066225 0.87 PDE10A (1.00) PDE10AMEN1MAPTKMT2A
SCHEMBL2646721 0.83 PDE10A (0.69) PDE10AMEN1MAPTKMT2A
SCHEMBL6851771 0.80 PDE10A (0.77) PDE10AMEN1MAPTKMT2A
SCHEMBL7317281 0.80 PDE10A (0.77) PDE10AMEN1MAPTKMT2A
SCHEMBL12471341 0.80 PDE10A (0.77) PDE10AMEN1MAPTKMT2A
SCHEMBL7317271 0.80 PDE10A (0.77) PDE10AMEN1MAPTKMT2A
SCHEMBL9971272 0.80 PDE10A (0.77) PDE10AMEN1MAPTKMT2A
SCHEMBL8408826 0.80 PDE10A (0.77) PDE10AMEN1MAPTKMT2A
SCHEMBL28237594 0.78 PDE10A (0.81) PDE10AMEN1MAPTKMT2A
SCHEMBL7068584 0.77 PDE10A (0.71) PDE10AMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110975941-B Hydroformylation reaction catalyst composition and method for preparing aldehyde through propylene hydroformylation reaction 万华化学集团股份有限公司 2022-08-05 CN disclosed
CN-110975941-A Hydroformylation reaction catalyst composition and method for preparing aldehyde through propylene hydroformylation reaction 万华化学集团股份有限公司 2020-04-10 CN disclosed
CN-103534256-B Macrocyclic hepatitis c serine protease inhibitors 益安药业 2016-08-10 CN disclosed
WO-2015042497-A2 SUBSTITUTED AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE CALITOR SCIENCES, LLC (US) 2015-03-26 WO disclosed
CN-104418849-A Substituted aminopyrimidine compound as well as using method and application thereof GUANGDONG HEC PHARMACEUTICAL 2015-03-18 CN disclosed