Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 17/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12066225 | 0.87 | PDE10A (1.00) | PDE10AMEN1MAPTKMT2A | |
| SCHEMBL752676 | 0.83 | PDE10A (0.69) | PDE10AMEN1MAPTKMT2A | |
| SCHEMBL7317281 | 0.80 | PDE10A (0.77) | PDE10AMEN1MAPTKMT2A | |
| SCHEMBL7317271 | 0.80 | PDE10A (0.77) | PDE10AMEN1MAPTKMT2A | |
| SCHEMBL12471341 | 0.80 | PDE10A (0.77) | PDE10AMEN1MAPTKMT2A | |
| SCHEMBL9971272 | 0.80 | PDE10A (0.77) | PDE10AMEN1MAPTKMT2A | |
| SCHEMBL16585358 | 0.80 | PDE10A (0.77) | PDE10AMEN1MAPTKMT2A | |
| SCHEMBL8408826 | 0.80 | PDE10A (0.77) | PDE10AMEN1MAPTKMT2A | |
| SCHEMBL28237594 | 0.78 | PDE10A (0.81) | PDE10AMEN1MAPTKMT2A | |
| SCHEMBL7071801 | 0.77 | PDE10A (0.71) | PDE10AMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585775-A | 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials | ORTHO MCNEIL PHARM INC (US) | 2005-02-23 | — | — | CN | disclosed |
| US-6825170-B2 | ERYTHROMYCIN TYPE MACROLIDE WITH A FUSED OXAZOLONE RING | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-11-30 | — | — | US | disclosed |
| EP-1453847-A1 | 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003050132-A1 | 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2003-06-19 | — | — | WO | disclosed |
| US-5719291-A | FUNGICIDE | HOFFMANN-LA ROCHE INC. (US) | 1998-02-17 | — | — | US | disclosed |
| US-5449785-A | Fungicides with triazole groups | HOFFMANN-LA ROCHE INC. (US) | 1995-09-12 | — | — | US | disclosed |
| CN-1069976-A | Hexanaphthene and tetrahydropyran derivatives | HOFFMANN LA ROCHE (CH) | 1993-03-17 | — | — | CN | disclosed |