Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 6/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TYR | P14679 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18585793 | 1.00 | SERPINE1 (0.59) | SERPINE1PTPN1PTPN2PTPN11ESR1 | |
| SCHEMBL18585722 | 0.98 | SERPINE1 (0.58) | SERPINE1PTPN1PTPN2PTPN11ESR1 | |
| SCHEMBL18585433 | 0.97 | SERPINE1 (0.59) | SERPINE1PTPN1PTPN2PTPN11ESR1 | |
| SCHEMBL18585589 | 0.90 | SERPINE1 (0.63) | SERPINE1PTPN1PTPN2PTPN11ESR1 | |
| SCHEMBL16144965 | 0.88 | SERPINE1 (0.61) | SERPINE1PTPN1PTPN2PTPN11ESR1 | |
| SCHEMBL16144977 | 0.88 | SERPINE1 (0.61) | SERPINE1PTPN1PTPN2PTPN11ESR1 | |
| SCHEMBL16144972 | 0.87 | SERPINE1 (0.63) | SERPINE1PTPN1PTPN2PTPN11ESR1 | |
| SCHEMBL2731285 | 0.85 | SERPINE1 (0.54) | SERPINE1PTPN1PTPN2PTPN11ESR1 | |
| SCHEMBL28044238 | 0.85 | SERPINE1 (0.54) | SERPINE1PTPN1PTPN2PTPN11ESR1 | |
| SCHEMBL17779375 | 0.85 | PTPN1 (0.61) | SERPINE1PTPN1PTPN2PTPN11ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3046572-A1 | CHLOROTOXIN CONJUGATES AND METHODS OF USE THEREOF | Blaze Bioscience, Inc. (US) | 2016-07-27 | — | — | EP | disclosed |
| WO-2015042202-A1 | CHLOROTOXIN CONJUGATES AND METHODS OF USE THEREOF | Blaze Bioscience, Inc. (US) | 2015-03-26 | — | — | WO | disclosed |