SCHEMBL28044238

SCHEMBL28044238

O=C(OCC(O)C(O)C(O)C(O)C(=O)CO)c1cc(O)c(O)c(O)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SERPINE1 P05121 6/20 0.54
PTPN2 P17706 1/20 0.45
PTPN1 P18031 1/20 0.45
PTPN11 Q06124 1/20 0.45
ESR1 P03372 2/20 0.42
AKR1C4 P17516 1/20 0.40
AKR1C3 P42330 1/20 0.40
AKR1C2 P52895 1/20 0.40
AKR1C1 Q04828 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
TYR P14679 2/20 0.40
ALDH1A1 P00352 1/20 0.40
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39
POLB P06746 1/20 0.39
GAA P10253 1/20 0.39
NFKB1 P19838 1/20 0.39
XDH P47989 1/20 0.39
GFER P55789 1/20 0.39
NFKB2 Q00653 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2731285 1.00 SERPINE1 (0.54) SERPINE1PTPN2PTPN1PTPN11ESR1
SCHEMBL18585793 0.85 SERPINE1 (0.59) SERPINE1PTPN2PTPN1PTPN11ESR1
SCHEMBL16585686 0.85 SERPINE1 (0.59) SERPINE1PTPN2PTPN1PTPN11ESR1
SCHEMBL18585722 0.84 SERPINE1 (0.58) SERPINE1PTPN2PTPN1PTPN11ESR1
SCHEMBL17157078 0.83 SERPINE1 (0.54) SERPINE1PTPN2PTPN1PTPN11ESR1
SCHEMBL18585433 0.82 SERPINE1 (0.59) SERPINE1PTPN2PTPN1PTPN11ESR1
SCHEMBL18585589 0.79 SERPINE1 (0.63) SERPINE1PTPN2PTPN1PTPN11ESR1
SCHEMBL3228891 0.79 SERPINE1 (0.55) SERPINE1PTPN2PTPN1PTPN11ESR1
SCHEMBL20578289 0.79 SERPINE1 (0.55) SERPINE1PTPN2PTPN1PTPN11ESR1
SCHEMBL11986809 0.77 SERPINE1 (0.46) SERPINE1PTPN2PTPN1PTPN11ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105307659-A Use of sedoheptulose as a nutritional supplement UNIV WIEN MED 2016-02-03 CN disclosed
CN-105283188-A Use of sedoheptulose for preventing or treating inflammation UNIV WIEN MED 2016-01-27 CN disclosed