Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.32 |
| ▸ | FLT4 | P35916 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CCR4 | P51679 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16597072 | 0.76 | PPARA (0.33) | AOC3PPARAGABRA1GABRG2GABRB3 | |
| SCHEMBL16584083 | 0.74 | NPC1 (0.34) | PDPK1FLT4KDR | |
| SCHEMBL20969942 | 0.73 | PPARA (0.40) | AOC3PPARAGABRA1GABRG2GABRB3 | |
| SCHEMBL7676249 | 0.70 | HRH4 (0.36) | — | |
| SCHEMBL16583426 | 0.68 | PDE10A (0.33) | FLT4KDR | |
| SCHEMBL16583549 | 0.68 | FLT4 (0.33) | FLT4KDR | |
| SCHEMBL13696876 | 0.68 | CLK4 (0.53) | AOC3ALDH1A1 | |
| SCHEMBL18076627 | 0.67 | NPC1 (0.38) | PDPK1ALDH1A1 | |
| SCHEMBL2629321 | 0.66 | — | — | |
| SCHEMBL16583445 | 0.65 | ALDH1A1 (0.35) | PDPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104418849-B | Substituted aminopyrimidine compounds and use method and application thereof | 广东东阳光药业有限公司 | 2020-04-21 | — | — | CN | disclosed |
| WO-2015042497-A2 | SUBSTITUTED AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE | CALITOR SCIENCES, LLC (US) | 2015-03-26 | — | — | WO | disclosed |
| WO-2015042497-A2 | SUBSTITUTED AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE | CALITOR SCIENCES, LLC (US) | 2015-03-26 | — | — | WO | disclosed |