Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.67 |
| ▸ | ATIC | P31939 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.55 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.55 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.55 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PTPRA | P18433 | 1/20 | 0.50 |
| ▸ | PTPRB | P23467 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16587015 | 1.00 | PHLPP2 (0.67) | PHLPP2ATICMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL9324859 | 0.85 | SUMO2 (0.75) | PHLPP2ATICMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL14418370 | 0.85 | SUMO2 (0.75) | PHLPP2ATICMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL29860575 | 0.83 | PHLPP2 (0.55) | PHLPP2ATICMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL11336943 | 0.81 | MAPT (0.80) | ATICMAPK1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL4412992 | 0.81 | MAPT (0.80) | ATICMAPK1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL109165 | 0.81 | MAPT (0.80) | ATICMAPK1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL92162 | 0.81 | MAPT (0.80) | ATICMAPK1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL29376978 | 0.81 | MAPT (0.80) | ATICMAPK1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL1098585 | 0.81 | APP (0.69) | PHLPP2MAPK1ALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150086487-A1 | LIQUID ACTIVATION SYSTEM | COLGATE PALMOLIVE CO (US) | 2015-03-26 | — | — | US | disclosed |