SCHEMBL4412992

SCHEMBL4412992

O=S(=O)(O)c1ccc(N=Nc2ccc(N=Nc3c(O)ccc4ccccc34)cc2)cc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.80
KMT2A Q03164 5/20 0.80
MEN1 O00255 4/20 0.80
TDP1 Q9NUW8 4/20 0.74
MAPK1 P28482 3/20 0.74
GAA P10253 2/20 0.74
L3MBTL1 Q9Y468 2/20 0.68
LMNA P02545 1/20 0.68
ALPL P05186 1/20 0.68
HSP90AA1 P07900 1/20 0.68
ALPI P09923 1/20 0.68
ALPG P10696 1/20 0.68
CASP3 P42574 1/20 0.68
RECQL P46063 1/20 0.68
MMP14 P50281 1/20 0.68
SENP8 Q96LD8 1/20 0.68
SENP7 Q9BQF6 1/20 0.68
SENP6 Q9GZR1 1/20 0.68
THRB P10828 4/20 0.68
CYP1A2 P05177 2/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL92162 1.00 MAPT (0.80) MAPTKMT2AMEN1TDP1MAPK1
SCHEMBL11336943 1.00 MAPT (0.80) MAPTKMT2AMEN1TDP1MAPK1
SCHEMBL29376978 1.00 MAPT (0.80) MAPTKMT2AMEN1TDP1MAPK1
SCHEMBL109165 1.00 MAPT (0.80) MAPTKMT2AMEN1TDP1MAPK1
SCHEMBL30842302 0.99 MAPT (0.78) MAPTKMT2AMEN1TDP1MAPK1
SCHEMBL144505 0.99 MAPT (0.78) MAPTKMT2AMEN1TDP1MAPK1
SCHEMBL144503 0.99 MAPT (0.78) MAPTKMT2AMEN1TDP1MAPK1
SCHEMBL19000765 0.89 MAPT (0.79) MAPTKMT2AMEN1TDP1MAPK1
SCHEMBL11877643 0.88 MAPT (0.66) MAPTKMT2AMEN1TDP1MAPK1
SCHEMBL11877650 0.88 MAPT (0.66) MAPTKMT2AMEN1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7294370-B2 Polarizing and optical compensating films for visible, ultraviolet and infrared parts of the electromagnetic spectrum KENT STATE UNIVERSITY (US) 2007-11-13 US claimed
US-11384381-B2 Reaction accelerating agent KIKKOMAN CORPORATION (JP) 2022-07-12 US disclosed
US-20190316174-A1 REACTION ACCELERATING AGENT KIKKOMAN CORPORATION (JP) 2019-10-17 US disclosed
US-9150788-B2 Non-amphiphile-based water-in-water emulsion and uses thereof SYRACUSE UNIVERSITY (US) 2015-10-06 US disclosed
US-20090269323-A1 NON-AMPHIPHILE-BASED WATER-IN-WATER EMULSION AND USES THEREOF SYRACUSE UNIVERSITY TECHNOLOGY TRANSFER AND INDUSTRIAL DEVELOPMENT OFFICE (US) 2009-10-29 US disclosed
US-7294370-B2 Polarizing and optical compensating films for visible, ultraviolet and infrared parts of the electromagnetic spectrum KENT STATE UNIVERSITY (US) 2007-11-13 US disclosed
US-4248777-A DIAZOTIZATION OF AMINOAZOBENZENE SULFONATE AND COUPLING WITH 2-NAPHTHOL TO PRODUCE NON-GELLING STABLE DYE AMERICAN COLOR & CHEMICAL CORP. (US) 1981-02-03 US disclosed
US-4063880-A ANIONIC AND NONIONIC E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-12-20 US disclosed
US-4058607-A DIHALOVINYL DIALKYL PHOSPHATE, 1,3-BENZODIOXOLES AIRWICK INDUSTRIES, INC. (US) 1977-11-15 US disclosed
US-3966900-A INSECTICIDES AIRWICK INDUSTRIES, INC. (US) 1976-06-29 US disclosed
US-3957425-A DISAZO DYES, SOLVENT DYES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090269323-A1 NON-AMPHIPHILE-BASED WATER-IN-WATER EMULSION AND USES THEREOF FRG1, MAFG, AREG MAPT 3030/4885KMT2A 3235/4885MEN1 2286/4885
US-11384381-B2 Reaction accelerating agent MPO, AOX1, MAOA MAPT 4544/4885KMT2A 1992/4885MEN1 3767/4885
US-20190316174-A1 REACTION ACCELERATING AGENT MPO, AOX1, MAOA MAPT 4544/4885KMT2A 1992/4885MEN1 3767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.