Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16588388 | 0.89 | KMT2A (0.48) | KMT2AALDH1A1RAB9AKDM4ELMNA | |
| SCHEMBL13843636 | 0.82 | ALDH1A1 (0.47) | KMT2AALDH1A1RAB9AKDM4ELMNA | |
| SCHEMBL7261352 | 0.82 | ALDH1A1 (0.47) | KMT2AALDH1A1RAB9AKDM4ELMNA | |
| SCHEMBL6287263 | 0.81 | KMT2A (0.46) | KMT2AALDH1A1RAB9AKDM4ELMNA | |
| SCHEMBL1446116 | 0.80 | ALDH1A1 (0.43) | KMT2AALDH1A1RAB9AKDM4ELMNA | |
| SCHEMBL14426104 | 0.80 | KMT2A (0.41) | KMT2AALDH1A1RAB9AKDM4ELMNA | |
| SCHEMBL2118226 | 0.80 | ALDH1A1 (0.46) | KMT2AALDH1A1RAB9AKDM4ELMNA | |
| SCHEMBL11173610 | 0.80 | ALDH1A1 (0.46) | KMT2AALDH1A1RAB9AKDM4ELMNA | |
| SCHEMBL6285538 | 0.79 | KMT2A (0.43) | KMT2AALDH1A1RAB9AKDM4ELMNA | |
| SCHEMBL4465738 | 0.79 | KMT2A (0.40) | KMT2AALDH1A1RAB9AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2625169-B1 | QUINAZOLINE COMPOUNDS AS SODIUM CHANNEL BLOCKERS | PURDUE PHARMA LP (US) | 2015-03-25 | — | — | EP | disclosed |