Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16588792 | 0.92 | CA1 (0.35) | KCNA3CA1CA9CYP3A4ALDH1A1 | |
| SCHEMBL14741953 | 0.89 | CA1 (0.41) | KCNA3CA1CA9MEN1KMT2A | |
| SCHEMBL14741786 | 0.85 | CYP2D6 (0.38) | KCNA3MEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL14741833 | 0.83 | USP2 (0.33) | KCNA3CYP3A4ALDH1A1CCR5SLC6A2 | |
| SCHEMBL16588788 | 0.82 | CA1 (0.34) | KCNA3CA1CA9MEN1KMT2A | |
| SCHEMBL14741940 | 0.81 | KCNA3 (0.39) | KCNA3CA1CA9MEN1KMT2A | |
| SCHEMBL14741836 | 0.81 | KCNA3 (0.36) | KCNA3CA1CA9MEN1KMT2A | |
| SCHEMBL16588831 | 0.80 | CA1 (0.33) | CA1CA9MEN1KMT2AALDH1A1 | |
| SCHEMBL16588818 | 0.79 | KCNA3 (0.38) | KCNA3CA1CA9MEN1KMT2A | |
| SCHEMBL30036856 | 0.78 | KCNA3 (0.47) | KCNA3MEN1KMT2ACYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993683-B2 | Polymers functionalized with lactones or thiolactones containing a protected amino group | BRIDGESTONE CORPORATION (JP) | 2015-03-31 | — | — | US | claimed |
| EP-2751142-B1 | POLYMERS FUNCTIONALIZED WITH LACTONES OR THIOLACTONES CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORP (JP) | 2015-12-09 | — | — | EP | disclosed |
| US-8993683-B2 | Polymers functionalized with lactones or thiolactones containing a protected amino group | BRIDGESTONE CORPORATION (JP) | 2015-03-31 | — | — | US | disclosed |