Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 7/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16588672 | 0.92 | KCNA3 (0.39) | CA1CA9CCR5SLC6A2SLC6A4 | |
| SCHEMBL14741953 | 0.90 | CA1 (0.41) | CA1CA9CCR5SLC6A2SLC6A4 | |
| SCHEMBL14741833 | 0.85 | USP2 (0.33) | CCR5SLC6A2SLC6A4KCNA3ALDH1A1 | |
| SCHEMBL16588653 | 0.85 | SLC6A2 (0.35) | CCR5SLC6A2SLC6A4KCNA3CTRB1 | |
| SCHEMBL16588779 | 0.81 | CTRB1 (0.33) | CA1CA9CTRB1ALDH1A1 | |
| SCHEMBL16588804 | 0.79 | CTRB1 (0.31) | CA1CA9CTRB1 | |
| SCHEMBL21047840 | 0.78 | SLC6A2 (0.39) | CCR5SLC6A2SLC6A4KCNA3ALDH1A1 | |
| SCHEMBL14741786 | 0.77 | CYP2D6 (0.38) | CCR5SLC6A2SLC6A4KCNA3ALDH1A1 | |
| SCHEMBL14741925 | 0.76 | CA1 (0.32) | CA1CA9CTRB1 | |
| SCHEMBL14741836 | 0.75 | KCNA3 (0.36) | CA1CA9CCR5KCNA3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993683-B2 | Polymers functionalized with lactones or thiolactones containing a protected amino group | BRIDGESTONE CORPORATION (JP) | 2015-03-31 | — | — | US | claimed |
| CN-103857704-A | Polymers functionalized with lactones or thiolactones containing a protected amino group | BRIDGESTONE CORP | 2014-06-11 | — | — | CN | claimed |
| CN-103857704-B | By the lactone containing shielded amino or the functionalized polymkeric substance of thiolactone | BRIDGESTONE CO.,LTD. (JP) | 2016-02-17 | — | — | CN | disclosed |
| EP-2751142-B1 | POLYMERS FUNCTIONALIZED WITH LACTONES OR THIOLACTONES CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORP (JP) | 2015-12-09 | — | — | EP | disclosed |
| US-8993683-B2 | Polymers functionalized with lactones or thiolactones containing a protected amino group | BRIDGESTONE CORPORATION (JP) | 2015-03-31 | — | — | US | disclosed |
| CN-103857704-A | Polymers functionalized with lactones or thiolactones containing a protected amino group | BRIDGESTONE CORP | 2014-06-11 | — | — | CN | disclosed |