Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMEL1 | Q495T6 | 11/20 | 0.51 |
| ▸ | MME | P08473 | 10/20 | 0.48 |
| ▸ | ACE | P12821 | 5/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3703250 | 1.00 | MMEL1 (0.51) | MMEL1MMEACECTSL | |
| SCHEMBL17751396 | 0.90 | MME (0.48) | MMEL1MMEACE | |
| SCHEMBL2779890 | 0.90 | MMEL1 (0.62) | MMEL1MMEACECTSL | |
| SCHEMBL2779899 | 0.90 | MMEL1 (0.62) | MMEL1MMEACECTSL | |
| SCHEMBL12975086 | 0.86 | MMEL1 (0.59) | MMEL1MMEACECTSL | |
| SCHEMBL8532740 | 0.85 | MMEL1 (0.53) | MMEL1MMEACECTSL | |
| SCHEMBL6122512 | 0.85 | MMEL1 (0.53) | MMEL1MMEACECTSL | |
| SCHEMBL12999642 | 0.85 | MMEL1 (0.55) | MMEL1MMEACECTSL | |
| SCHEMBL12975705 | 0.85 | MMEL1 (0.55) | MMEL1MMEACECTSL | |
| SCHEMBL12975100 | 0.85 | MMEL1 (0.67) | MMEL1MMEACECTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993631-B2 | Method of treating contrast-induced nephropathy | NOVARTIS AG (CH) | 2015-03-31 | — | — | US | disclosed |