SCHEMBL16590664

SCHEMBL16590664

C=CCO[C@H]1OC(C)[C@H](O)C(C)[C@H]1C

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FUCA1 P04066 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13079297 0.89 FUCA1 (0.30) FUCA1
SCHEMBL17773549 0.89 FUCA1 (0.33) FUCA1
SCHEMBL17773540 0.89 FUCA1 (0.33) FUCA1
SCHEMBL18305015 0.84 L3MBTL1 (0.36) FUCA1
SCHEMBL13079298 0.84 L3MBTL1 (0.36) FUCA1
SCHEMBL18940518 0.84 L3MBTL1 (0.36) FUCA1
SCHEMBL5670720 0.84 L3MBTL1 (0.36) FUCA1
SCHEMBL11277134 0.84 L3MBTL1 (0.36) FUCA1
SCHEMBL1119069 0.84 L3MBTL1 (0.36) FUCA1
SCHEMBL2046273 0.84 L3MBTL1 (0.36) FUCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230131867-A1 TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF SLOAN KETTERING INST CANCER RES (US) 2023-04-27 — — US disclosed
US-20170283450-A1 TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF MEMORIAL SLOAN-KETTERING INST FOR CANCER RES (US) 2017-10-05 — — US disclosed
US-9718850-B2 Triterpene saponins, methods of synthesis and uses thereof MEMORIAL SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 2017-08-01 — — US disclosed
US-20150086585-A1 TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF MEMORIAL SLOAN KETTERING INST FOR CANCER RES (US) 2015-03-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230131867-A1 TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF LSS, CYP51A1, TLR7 FUCA1 766/4885
US-20150086585-A1 TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF LSS, CYP51A1, TLR7 FUCA1 766/4885
US-20170283450-A1 TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF LSS, CYP51A1, TLR7 FUCA1 766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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