SCHEMBL16592186

SCHEMBL16592186

CON1CCC2(CC1)OC(C)=C(c1cc(C)ccc1C)C2=O

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.35
TP53 P04637 1/20 0.34
POLB P06746 1/20 0.34
AVPR1A P37288 5/20 0.33
KDM4E B2RXH2 2/20 0.33
HTR2C P28335 1/20 0.33
ATM Q13315 2/20 0.33
HTT P42858 1/20 0.33
MAPT P10636 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
KMT2A Q03164 1/20 0.32
NPY5R Q15761 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL768905 0.82 POLB (0.39) HSD11B1POLBAVPR1AKDM4EMAPT
SCHEMBL16592190 0.79 SIGMAR1 (0.41) POLB
SCHEMBL16592191 0.78 KMT2A (0.38) TP53POLBKDM4EHTTMEN1
SCHEMBL769586 0.75 POLB (0.36) POLBAVPR1AHTTMAPTMEN1
SCHEMBL782486 0.75 POLB (0.36) POLBAVPR1AATMMAPTMEN1
SCHEMBL16585741 0.74 KDM4E (0.33) HSD11B1TP53POLBAVPR1AKDM4E
SCHEMBL2759740 0.73 ACACB (0.39) TP53MAPTKMT2A
SCHEMBL249181 0.73 ACACB (0.53) MEN1ALDH1A1HPGDKMT2ACA1
SCHEMBL29735375 0.73 ACACB (0.53) MEN1ALDH1A1HPGDKMT2ACA1
SCHEMBL16592187 0.72 TP53 (0.32) TP53HTR2CALDH1A1KMT2ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015040406-A2 AGRICULTURAL CHEMICALS REDX PHARMA LIMITED (GB) 2015-03-26 WO disclosed