Thiophene

Thiophene

SCHEMBL16596106

CCOc1cscc1OCC.COc1cscc1OC.c1ccsc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.41
MAPT P10636 2/20 0.41
GAA P10253 1/20 0.41
ALDH1A1 P00352 2/20 0.34
TSHR P16473 2/20 0.34
KMT2A Q03164 1/20 0.34
CALM1 P0DP23 2/20 0.33
MAPK1 P28482 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
HTR2B P41595 1/20 0.33
SYK P43405 1/20 0.32
PDE4A P27815 2/20 0.32
PDE4B Q07343 2/20 0.32
PDE4C Q08493 2/20 0.32
PDE4D Q08499 2/20 0.32
ENPP1 P22413 1/20 0.32
KCNK3 O14649 1/20 0.31
KCNK9 Q9NPC2 1/20 0.31
L3MBTL1 Q9Y468 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9298156 0.90 KDM4E (0.47) KDM4EMAPTGAAALDH1A1TSHR
SCHEMBL740846 0.81 NQO1 (0.41) KDM4EMAPTGAAALDH1A1TSHR
Ethylene SCHEMBL29270267 0.77 ALDH1A1 (0.38) KDM4EMAPTGAAALDH1A1TSHR
SCHEMBL15387235 0.74 KDM4E (0.34) KDM4EMAPTGAAHTR2AHTR2C
SCHEMBL12345499 0.74 ALDH1A1 (0.40) KDM4EMAPTGAAALDH1A1KMT2A
SCHEMBL9298158 0.72 CYP1A2 (0.41) ALDH1A1PDE4APDE4BPDE4CPDE4D
Water SCHEMBL27790537 0.71 CA1 (0.40) KDM4EMAPTGAAALDH1A1TSHR
Ammonia Solution, Strong SCHEMBL28304171 0.71 CA1 (0.40) KDM4EMAPTGAAALDH1A1TSHR
SCHEMBL9510191 0.71 SMPD1 (0.41) MAPTALDH1A1TSHRKMT2AHTR2B
SCHEMBL9511301 0.69 SMPD1 (0.43) MAPTALDH1A1TSHRKMT2AHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015043182-A1 ELECTROCHROMIC MATERIAL, PREPARATION METHOD THEREFOR, AND ASSEMBLY THEREOF 京东方科技集团股份有限公司 2015-04-02 WO disclosed
CN-103524718-A Red electrochromic material and preparation method and assembly thereof BOE TECHNOLOGY GROUP CO LTD 2014-01-22 CN disclosed