Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 1/20 | 0.54 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16596226 | 0.82 | HSD17B10 (0.48) | CA1CA2CA7CA14 | |
| SCHEMBL16596235 | 0.80 | SMARCA2 (0.52) | SMARCA2SMARCA4CA1CA2CA7 | |
| SCHEMBL25841409 | 0.80 | SMARCA2 (0.59) | SMARCA2SMARCA4MALT1MGLL | |
| SCHEMBL24974005 | 0.80 | EPHX2 (0.59) | CA1CA2CA7CA14 | |
| SCHEMBL26938529 | 0.80 | SMARCA2 (0.56) | SMARCA2SMARCA4FAAHMGLL | |
| SCHEMBL18626324 | 0.79 | SMARCA2 (0.55) | SMARCA2SMARCA4MALT1CA1CA2 | |
| SCHEMBL24258152 | 0.78 | SMARCA2 (0.64) | SMARCA2SMARCA4MGLL | |
| SCHEMBL19308413 | 0.78 | SMARCA2 (0.57) | SMARCA2SMARCA4CA1CA2MGLL | |
| SCHEMBL23593331 | 0.78 | SMARCA2 (0.43) | SMARCA2SMARCA4FAAHMALT1MGLL | |
| SCHEMBL23593396 | 0.78 | SMARCA2 (0.43) | SMARCA2SMARCA4FAAHMALT1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015042363-A1 | MOLECULES AND COMPOSITIONS THAT INHIBIT GRAM NEGATIVE BACTERIA AND THEIR USES | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2015-03-26 | — | — | WO | disclosed |