Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.58 |
| ▸ | APP | P05067 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | NQO2 | P16083 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16596255 | 0.92 | ENPP2 (0.54) | ENPP2APPMAPTSMN1; SMN2TP53 | |
| SCHEMBL16596308 | 0.91 | ENPP2 (0.57) | ENPP2APPMAPTSMN1; SMN2TP53 | |
| SCHEMBL17958358 | 0.91 | ENPP2 (0.70) | ENPP2APPMAPTSMN1; SMN2TP53 | |
| SCHEMBL16596286 | 0.91 | ENPP2 (0.70) | ENPP2APPMAPTSMN1; SMN2TP53 | |
| SCHEMBL17971236 | 0.91 | ENPP2 (0.58) | ENPP2APPMAPTSMN1; SMN2TP53 | |
| SCHEMBL16596381 | 0.86 | ENPP2 (0.51) | ENPP2APPMAPTSMN1; SMN2TP53 | |
| SCHEMBL19156159 | 0.85 | ENPP2 (0.61) | ENPP2APPMAPTSMN1; SMN2TP53 | |
| SCHEMBL17975419 | 0.83 | ENPP2 (0.65) | ENPP2APPPOLBSNCAALDH1A1 | |
| SCHEMBL17958334 | 0.82 | ENPP2 (0.69) | ENPP2APPMAPTSMN1; SMN2TP53 | |
| SCHEMBL16596242 | 0.82 | ENPP2 (0.69) | ENPP2APPMAPTSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015042053-A1 | VINYL AUTOTAXIN INHIBITOR COMPOUNDS | PHARMAKEA, INC. (US) | 2015-03-26 | — | — | WO | disclosed |