SCHEMBL1659833

SCHEMBL1659833

O=C(C=Cc1ccc(Br)cc1)c1ccc(Br)cc1

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.86
ESR2 Q92731 1/20 0.86
CYP1B1 Q16678 2/20 0.82
MAPT P10636 4/20 0.75
MAOB P27338 4/20 0.75
MAOA P21397 1/20 0.75
RECQL P46063 2/20 0.69
MEN1 O00255 1/20 0.69
USP2 O75604 1/20 0.69
ALDH1A1 P00352 1/20 0.69
POLB P06746 1/20 0.69
MAPK1 P28482 1/20 0.69
KMT2A Q03164 1/20 0.69
TLR9 Q9NR96 1/20 0.69
TDP1 Q9NUW8 1/20 0.69
L3MBTL1 Q9Y468 1/20 0.69
F3 P13726 2/20 0.68
PTPN1 P18031 1/20 0.68
TNFRSF1A P19438 2/20 0.66
P4HB P07237 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1659832 1.00 ESR1 (0.86) ESR1ESR2CYP1B1MAPTMAOB
SCHEMBL17694974 0.94 ESR1 (0.77) ESR1ESR2CYP1B1MAPTMAOB
SCHEMBL25212485 0.93 CYP1B1 (0.77) ESR1ESR2CYP1B1MAPTMAOB
SCHEMBL25203783 0.93 CYP1B1 (0.77) ESR1ESR2CYP1B1MAPTMAOB
SCHEMBL3268064 0.93 CYP1B1 (0.77) ESR1ESR2CYP1B1MAPTMAOB
SCHEMBL25200521 0.93 CYP1B1 (0.77) ESR1ESR2CYP1B1MAPTMAOB
SCHEMBL25223617 0.93 CYP1B1 (0.77) ESR1ESR2CYP1B1MAPTMAOB
SCHEMBL25221605 0.93 ESR1 (1.00) ESR1ESR2CYP1B1MAPTMAOB
SCHEMBL25221606 0.93 ESR1 (1.00) ESR1ESR2CYP1B1MAPTMAOB
SCHEMBL25195374 0.93 CYP1B1 (0.77) ESR1ESR2CYP1B1MAPTMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240334821-A1 Electroluminescent Device UDC IRELAND LTD (IE) 2024-10-03 US disclosed
US-11968893-B2 Electroluminescent device UDC IRELAND LIMITED (IE) 2024-04-23 US disclosed
CN-114524829-B Preparation method of imidazo [2,1-b ] thiazole derivative 新疆大学 2024-04-02 CN disclosed
US-20220216422-A1 Electroluminescent Device UDC IRELAND LTD (IE) 2022-07-07 US disclosed
CN-114524829-A Preparation method of imidazo [2,1-b ] thiazole derivative 新疆大学 2022-05-24 CN disclosed
US-11289658-B2 Electroluminescent device UDC IRELAND LIMITED (IE) 2022-03-29 US disclosed
US-20180269403-A1 ELECTROLUMINESCENT DEVICE UDC IRELAND LTD (IE) 2018-09-20 US disclosed
US-9923148-B2 Electroluminescent device UDC IRELAND LIMITED (IE) 2018-03-20 US disclosed
US-20170194568-A9 Electroluminescent Device UDC IRELAND LIMITED (IE) 2017-07-06 US disclosed
US-9048442-B2 Composition containing a metal complex and organic compound, and light-emitting element using said compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-06-02 US disclosed
US-20130079517-A1 Electroluminescent Device BASF SE (DE) 2013-03-28 US disclosed
US-8012602-B2 Blue emitting, durable, organoelectroluminescent layers containing pyrimidine moieties; full color displays; light emission efficiency and brightness BASF SE (DE) 2011-09-06 US disclosed
US-20110114890-A1 COMPOSITION CONTAINING A METAL COMPLEX AND ORGANIC COMPOUND, AND LIGHT-EMITTING ELEMENT USING SAID COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-05-19 US disclosed
EP-2305772-A1 COMPOSITION CONTAINING A METAL COMPLEX AND ORGANIC COMPOUND, AND LIGHT EMITTING ELEMENT USING SAID COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-04-06 EP disclosed
US-20100240892-A1 ELECTROLUMINESCENT DEVICE SCHAEFER THOMAS 2010-09-23 US disclosed
US-20100039026-A1 Organic light emitting diode employing luminescent efficiency improvement layer SAMSUNG DISPLAY CO., LTD. (KR) 2010-02-18 US disclosed
EP-1556360-B1 ELECTROLUMINESCENT DEVICE CIBA SC HOLDING AG (CH) 2008-01-23 EP disclosed
US-7067702-B2 Process for preparing vinyl substituted beta-diketones THE JOHNS HOPKINS UNIVERSITY (US) 2006-06-27 US disclosed
US-20060069288-A1 Process for preparing vinyl substituted beta-diketones THE JOHNS HOPKINS UNIVERSITY 2006-03-30 US disclosed
US-20060041126-A1 Blue emitting, durable, organoelectroluminescent layers containing pyrimidine moieties; full color displays; light emission efficiency and brightness CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060041126-A1 Blue emitting, durable, organoelectroluminescent layers containing pyrimidine moieties; full color displays; light emission efficiency and brightness AXL, TK1, TYMP ESR1 919/4885ESR2 1867/4885CYP1B1 1587/4885
US-20240334821-A1 Electroluminescent Device PNPO, ODC1, AXL ESR1 805/4885ESR2 1217/4885CYP1B1 2432/4885
US-20180269403-A1 ELECTROLUMINESCENT DEVICE PNPO, ODC1, AXL ESR1 805/4885ESR2 1217/4885CYP1B1 2432/4885
US-20060069288-A1 Process for preparing vinyl substituted beta-diketones VRK1, VRK2, DEK ESR1 2229/4885ESR2 1662/4885CYP1B1 996/4885
US-11289658-B2 Electroluminescent device PNPO, ODC1, AXL ESR1 805/4885ESR2 1217/4885CYP1B1 2432/4885
US-20220216422-A1 Electroluminescent Device PNPO, ODC1, AXL ESR1 805/4885ESR2 1217/4885CYP1B1 2432/4885
US-20170194568-A9 Electroluminescent Device DPYD, PNPO, TYMP ESR1 653/4885ESR2 1121/4885CYP1B1 2122/4885
US-20130079517-A1 Electroluminescent Device DPYD, PNPO, TYMP ESR1 653/4885ESR2 1121/4885CYP1B1 2122/4885
US-11968893-B2 Electroluminescent device PNPO, ODC1, AXL ESR1 805/4885ESR2 1217/4885CYP1B1 2432/4885
US-20100240892-A1 ELECTROLUMINESCENT DEVICE PNPO, ODC1, AXL ESR1 805/4885ESR2 1217/4885CYP1B1 2432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.