⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylene Chloride SCHEMBL375336 | 1.00 | — | — | |
| Methylene Chloride SCHEMBL8405128 | 1.00 | ALDH1A1 (0.50) | — | |
| Methylene Chloride SCHEMBL214547 | 0.94 | — | — | |
| Methylene Chloride SCHEMBL4410896 | 0.94 | ALDH1A1 (0.44) | — | |
| Methylene Chloride SCHEMBL4784041 | 0.94 | ALDH1A1 (0.57) | — | |
| Methylene Chloride SCHEMBL2031974 | 0.94 | ALDH1A1 (0.57) | — | |
| Methylene Chloride SCHEMBL9625167 | 0.94 | ALDH1A1 (0.57) | — | |
| Methylene Chloride SCHEMBL1832445 | 0.94 | ALDH1A1 (0.57) | — | |
| Methylene Chloride SCHEMBL4933917 | 0.94 | ALDH1A1 (0.57) | — | |
| Methylene Chloride SCHEMBL292514 | 0.94 | ALDH1A1 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957266-B2 | Imidazo[1,2-a]pyridin-7-amine | HOFFMANN-LA ROCHE INC. (US) | 2018-05-01 | — | — | US | disclosed |
| EP-3049411-B1 | IMIDAZO[1,2-A]PYRIDIN-7-AMINES AS IMAGING TOOLS | HOFFMANN LA ROCHE (CH) | 2017-04-26 | — | — | EP | disclosed |
| EP-3049411-A1 | IMIDAZO[1,2-A]PYRIDIN-7-AMINES AS IMAGING TOOLS | F. Hoffmann-La Roche AG (CH) | 2016-08-03 | — | — | EP | disclosed |
| US-20160207919-A1 | IMIDAZO[1,2-a]PYRIDIN-7-AMINE | HOFFMANN-LA ROCHE INC. (US) | 2016-07-21 | — | — | US | disclosed |
| WO-2015044095-A1 | IMIDAZO[1,2-A]PYRIDIN-7-AMINES AS IMAGING TOOLS | F. HOFFMANN-LA ROCHE AG (CH) | 2015-04-02 | — | — | WO | disclosed |