Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.65 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.65 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.65 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.65 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19746141 | 0.92 | HDAC8 (0.66) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL16599867 | 0.90 | HDAC8 (0.75) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL16599868 | 0.90 | HDAC8 (0.75) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL16599690 | 0.89 | HDAC3 (0.60) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL16599696 | 0.89 | HDAC3 (0.60) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL16599842 | 0.88 | HDAC8 (0.75) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL16599674 | 0.86 | HDAC8 (0.67) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL16599913 | 0.85 | HDAC3 (0.62) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL16599912 | 0.85 | HDAC3 (0.62) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL16600137 | 0.85 | ITGB2 (0.66) | HDAC8HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015048306-A1 | NOVEL AGENTS TARGETING CYP51 | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-04-02 | — | — | WO | disclosed |