Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.66 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.66 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.66 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.66 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.66 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.66 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | FPR2 | P25090 | 2/20 | 0.60 |
| ▸ | FPR1 | P21462 | 1/20 | 0.60 |
| ▸ | ACE | P12821 | 1/20 | 0.59 |
| ▸ | TACR2 | P21452 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16600233 | 0.92 | HDAC8 (0.65) | HDAC8HDAC2HDAC6HDAC3HDAC4 | |
| SCHEMBL3787557 | 0.89 | MMP9 (0.72) | ACE | |
| SCHEMBL15139981 | 0.87 | ITGB2 (0.56) | HDAC8HDAC2HDAC6HDAC3HDAC4 | |
| SCHEMBL3782261 | 0.86 | KMT2A (0.66) | SMN1; SMN2MAPTACE | |
| SCHEMBL3857229 | 0.85 | ALOX15 (0.74) | FPR2ACE | |
| SCHEMBL3857226 | 0.85 | ALOX15 (0.74) | FPR2ACE | |
| SCHEMBL15576718 | 0.85 | GHSR (0.69) | HDAC8HDAC2HDAC6HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL20511893 | 0.85 | KMT2A (0.65) | MAPTACE | |
| Hydrochloric Acid SCHEMBL20511898 | 0.85 | KMT2A (0.65) | MAPTACE | |
| SCHEMBL22500577 | 0.85 | AIMP2 (0.73) | HDAC8HDAC2HDAC6HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11213512-B2 | Bis-amino acid based compound and use thereof | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2022-01-04 | — | — | US | disclosed |
| US-20190201379-A1 | BIS-AMINO ACID BASED COMPOUND AND USE THEREOF | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2019-07-04 | — | — | US | disclosed |
| WO-2017223098-A1 | BIS-AMINO ACID BASED COMPOUND AND USE THEREOF | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2017-12-28 | — | — | WO | disclosed |