Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 17/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16614212 | 0.99 | ENPP2 (0.64) | ENPP2NPC1ALDH1A1RAB9ANPSR1 | |
| SCHEMBL16600414 | 0.92 | ENPP2 (0.61) | ENPP2NPC1ALDH1A1RAB9ANPSR1 | |
| SCHEMBL16600530 | 0.89 | ENPP2 (0.58) | ENPP2ALDH1A1 | |
| SCHEMBL16600463 | 0.88 | ENPP2 (0.61) | ENPP2NPC1ALDH1A1RAB9A | |
| SCHEMBL17943014 | 0.87 | ENPP2 (0.61) | ENPP2NPC1ALDH1A1RAB9A | |
| SCHEMBL16600464 | 0.85 | ENPP2 (0.81) | ENPP2 | |
| SCHEMBL16614230 | 0.83 | ENPP2 (0.77) | ENPP2 | |
| SCHEMBL16600461 | 0.81 | ENPP2 (0.54) | ENPP2ALDH1A1 | |
| SCHEMBL17943189 | 0.80 | ENPP2 (0.85) | ENPP2 | |
| SCHEMBL16600595 | 0.79 | ENPP2 (0.65) | ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3049405-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | Pharmakea Inc. (US) | 2016-08-03 | — | — | EP | disclosed |
| WO-2015048301-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | PHARMAKEA, INC. (US) | 2015-04-02 | — | — | WO | disclosed |