Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29658020 | 0.93 | HCAR2 (0.41) | HCAR2TSHRTP53GPR84PLA2G4B | |
| SCHEMBL31557693 | 0.84 | SLC1A3 (0.31) | — | |
| SCHEMBL3369234 | 0.82 | TSHR (0.39) | ATMHCAR2ALDH1A1TSHRHPGD | |
| SCHEMBL26917674 | 0.81 | TSHR (0.42) | ATMHCAR2ALDH1A1TSHRHPGD | |
| SCHEMBL3339643 | 0.80 | PPARA (0.44) | PPARAPPARG | |
| SCHEMBL446035 | 0.80 | CYP4F2 (0.44) | ATMHCAR2ALDH1A1TSHRCPB1 | |
| SCHEMBL30609584 | 0.80 | TSHR (0.42) | ATMHCAR2TSHRCA2MAPK1 | |
| SCHEMBL28237464 | 0.79 | TSHR (0.41) | HCAR2ALDH1A1TSHRHPGDTP53 | |
| SCHEMBL445108 | 0.79 | CA2 (0.47) | ATMALDH1A1CPB1CPB2CA2 | |
| SCHEMBL445368 | 0.79 | PPARG (0.44) | ATMHCAR2ALDH1A1TSHRCPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003963-A1 | PYRAZOLE DERIVATIVES FOR CONTROLLING ARTHROPODS | Bayer Animal Health GmbH (DE) | 2022-06-01 | — | — | EP | disclosed |
| EP-3049390-A1 | SUBSTITUTED PHENYLALANINE DERIVATIVES | Bayer Pharma Aktiengesellschaft (DE) | 2016-08-03 | — | — | EP | disclosed |
| WO-2015044163-A1 | SUBSTITUTED PHENYLALANINE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-04-02 | — | — | WO | disclosed |