⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12764496 | 0.81 | — | — | |
| SCHEMBL10062532 | 0.77 | RAB9A (0.48) | — | |
| SCHEMBL1230092 | 0.77 | — | — | |
| SCHEMBL11483559 | 0.76 | CCR4 (0.46) | — | |
| SCHEMBL285537 | 0.75 | — | — | |
| SCHEMBL3131400 | 0.75 | — | — | |
| SCHEMBL2256127 | 0.75 | — | — | |
| SCHEMBL91500 | 0.75 | — | — | |
| SCHEMBL21962502 | 0.75 | — | — | |
| SCHEMBL2894565 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260062407-A1 | PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER | UNIV WAKE FOREST HEALTH SCIENCES (US) | 2026-03-05 | — | — | US | disclosed |
| US-20250381278-A1 | PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER | UNIV WAKE FOREST HEALTH SCIENCES (US) | 2025-12-18 | — | — | US | disclosed |
| EP-4577211-A2 | PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER | Wake Forest University Health Sciences (US) | 2025-07-02 | — | — | EP | disclosed |
| US-20250011316-A1 | PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER | WAKE FOREST UNIVERSITY HEALTH SCIENCES | 2025-01-09 | — | — | US | disclosed |
| WO-2024044744-A2 | PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2024-02-29 | — | — | WO | disclosed |
| US-11834449-B2 | TYK2 inhibitors and uses thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-12-05 | — | — | US | disclosed |
| US-11834449-B2 | TYK2 inhibitors and uses thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-12-05 | — | — | US | disclosed |
| US-20230242535-A1 | IMIDAZOTHIADIAZOLE AND IMIDAZOPYRAZINE DERIVATIVES AS PROTEASE ACTIVATED RECEPTOR 4 (PAR4) INHIBITORS FOR TREATING PLATELET AGGREGATION | BRISTOL MYERS SQUIBB CO (US) | 2023-08-03 | — | — | US | disclosed |
| US-20230219942-A1 | COMPOUNDS COMPRISING A THREE RING CORE AS PD-1/PD-L1 BLOCKERS | RELIVE THERAPEUTICS INC. (CA) | 2023-07-13 | — | — | US | disclosed |
| US-11053241-B2 | TYK2 inhibitors and uses thereof | NIMBUS LAKSHMI, INC. (US) | 2021-07-06 | — | — | US | disclosed |
| CN-101050204-A | Method for preparing compound of thiazole formaldehyde class | JIUZHOU PHARMA CO LTD ZHEJIANG (CN) | 2007-10-10 | — | — | CN | disclosed |
| US-7214801-B2 | Condensation reagents and a process for their preparation | LANXESS DEUTSCHLAND GMBH (DE) | 2007-05-08 | — | — | US | disclosed |
| CN-1310893-C | Condensation reagent and its preparation method | BAYER AG (DE) | 2007-04-18 | — | — | CN | disclosed |
| WO-2006130986-A1 | AZACYCLOHEXANE DERIVATIVES AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. (CA) | 2006-12-14 | — | — | WO | disclosed |
| US-7064216-B2 | Condensation reagents and a process for their preparation | BAYER AKTIENGESELLSCHAFT (DE) | 2006-06-20 | — | — | US | disclosed |
| EP-1216997-B1 | 2-bromo/chloro-thiazolium salts and their use as condensation agents | LANXESS DEUTSCHLAND GMBH (DE) | 2006-02-15 | — | — | EP | disclosed |
| US-20050267174-A1 | Condensation reagents and a process for their preparation | RUDOLPH JOACHIM | 2005-12-01 | — | — | US | disclosed |
| US-20020156287-A1 | Condensation reagents and a process for their preparation | LANXESS DEUTSCHLAND GMBH (DE) | 2002-10-24 | — | — | US | disclosed |
| CN-1365975-A | Condensation reagent and its preparation method | BAYER AG (DE) | 2002-08-28 | — | — | CN | disclosed |
| EP-1216997-A2 | 2-bromo/chloro-thiazolium salts and their use as condensation agents | BAYER AG (DE) | 2002-06-26 | — | — | EP | disclosed |