Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triphenylmethanol SCHEMBL700 | 0.82 | CYP19A1 (0.50) | TSHRCYP19A1CRHBPCRHR2CYP2C9 | |
| Diphenylmethanol SCHEMBL41571 | 0.82 | SMN1; SMN2 (0.61) | SMN1; SMN2L3MBTL1TSHRCA12CA1 | |
| Diphenylmethanol SCHEMBL11564700 | 0.82 | SMN1; SMN2 (0.61) | SMN1; SMN2L3MBTL1TSHRCA12CA1 | |
| Triphenylmethanol SCHEMBL1332873 | 0.82 | CYP19A1 (0.50) | TSHRCYP19A1CRHBPCRHR2CYP2C9 | |
| Diphenylmethanol SCHEMBL6434457 | 0.82 | SMN1; SMN2 (0.61) | SMN1; SMN2L3MBTL1TSHRCA12CA1 | |
| Triphenylmethanol SCHEMBL456603 | 0.82 | CYP19A1 (0.50) | TSHRCYP19A1CRHBPCRHR2CYP2C9 | |
| Diphenylmethanol SCHEMBL10868602 | 0.82 | SMN1; SMN2 (0.61) | SMN1; SMN2L3MBTL1TSHRCA12CA1 | |
| Diphenylmethanol SCHEMBL15641329 | 0.79 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1TSHRCA12CA1 | |
| Triphenylmethanol SCHEMBL1565321 | 0.79 | CYP19A1 (0.48) | TSHRCYP19A1CRHBPCRHR2CYP2C9 | |
| Diphenylmethanol SCHEMBL8164003 | 0.79 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1TSHRCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10350196-B2 | Long-acting spiro-isoxazoline formulations | ZOETIS SERVICES LLC (US) | 2019-07-16 | — | — | US | disclosed |
| US-20160235720-A1 | Long-Acting Spiro-Isoxazoline Formulations | ZOETIS SERVICES LLC | 2016-08-18 | — | — | US | disclosed |
| EP-3052080-A1 | LONG-ACTING SPIRO-ISOXAZOLINE FORMULATIONS | Zoetis Services LLC (US) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015048371-A1 | LONG-ACTING SPIRO-ISOXAZOLINE FORMULATIONS | ZOETIS LLC (US) | 2015-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160235720-A1 | Long-Acting Spiro-Isoxazoline Formulations | CYP2A7, CYP3A7, AVPR2 | SMN1; SMN2 1839/4885L3MBTL1 4773/4885TSHR 2598/4885 |
| US-10350196-B2 | Long-acting spiro-isoxazoline formulations | CYP2A7, CYP3A7, AVPR2 | SMN1; SMN2 1839/4885L3MBTL1 4773/4885TSHR 2598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.