SCHEMBL16601608

SCHEMBL16601608

CCc1cccc(CC)c1N1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(C)C3=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 2/20 0.59
DPP4 P27487 2/20 0.59
CRHBP P24387 1/20 0.49
CRHR2 Q13324 1/20 0.49
MEN1 O00255 5/20 0.45
KMT2A Q03164 5/20 0.45
ALDH1A1 P00352 4/20 0.45
HPGD P15428 4/20 0.45
USP2 O75604 3/20 0.45
KDM4E B2RXH2 3/20 0.45
KEAP1 Q14145 2/20 0.45
NFE2L2 Q16236 2/20 0.45
ATM Q13315 1/20 0.45
POLB P06746 2/20 0.43
PRMT1 Q99873 1/20 0.43
MAPT P10636 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
LMNA P02545 1/20 0.41
HTT P42858 1/20 0.41
CYP1A2 P05177 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16601630 0.94 ANPEP (0.54) ANPEPDPP4CRHBPCRHR2MEN1
SCHEMBL22221562 0.93 ANPEP (0.66) ANPEPDPP4CRHBPCRHR2MEN1
SCHEMBL12656452 0.91 DPP4 (0.50) ANPEPDPP4CRHBPCRHR2MEN1
SCHEMBL8070665 0.87 ANPEP (0.59) ANPEPDPP4CRHBPCRHR2MEN1
SCHEMBL16601631 0.86 DPP4 (0.46) ANPEPDPP4CRHBPCRHR2MEN1
SCHEMBL13045764 0.83 DPP4 (0.55) ANPEPDPP4CRHBPCRHR2MEN1
SCHEMBL24976892 0.82 ANPEP (0.51) ANPEPDPP4CRHBPCRHR2MEN1
SCHEMBL24453229 0.82 MEN1 (0.47) MEN1KMT2AALDH1A1HPGDUSP2
SCHEMBL30123663 0.81 ANPEP (0.60) ANPEPDPP4CRHBPCRHR2MEN1
SCHEMBL987346 0.80 DPP4 (0.68) ANPEPDPP4CRHBPCRHR2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4122930-A1 PHOTOELECRIC CONVERSION ELEMENT AND PHOTOELECRIC CONVERSION DEVICE COMPRISING SAID PHOTOELECRIC CONVERSION ELEMENT Canon Kabushiki Kaisha (JP) 2023-01-25 EP disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed