Sugi Predict

Sugi Predict / Compounds / SCHEMBL987346

SCHEMBL987346

SCHEMBL987346

CCc1cccc(CC)c1N1C(=O)c2ccccc2C1=O

nearest known ligand 0.68

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 4/20 0.68
▸ ANPEP P15144 2/20 0.68
▸ CRHBP P24387 1/20 0.60
▸ CRHR2 Q13324 1/20 0.60
▸ NR1H3 Q13133 4/20 0.50
▸ NR1H2 P55055 3/20 0.50
▸ KMT2A Q03164 3/20 0.46
▸ MEN1 O00255 2/20 0.46
▸ GAA P10253 1/20 0.46
▸ RAB9A P51151 1/20 0.46
▸ MGLL Q99685 1/20 0.46
▸ LMNA P02545 2/20 0.45
▸ MAPT P10636 1/20 0.45
▸ HTT P42858 1/20 0.45
▸ L3MBTL1 Q9Y468 1/20 0.45
▸ TSHR P16473 1/20 0.44
▸ POLB P06746 1/20 0.43
▸ NPEPPS P55786 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29382376 1.00 DPP4 (0.68) DPP4ANPEPCRHBPCRHR2NR1H3
SCHEMBL29381488 0.89 DPP4 (0.56) DPP4ANPEPCRHBPCRHR2NR1H3
SCHEMBL22221562 0.86 ANPEP (0.66) DPP4ANPEPCRHBPCRHR2KMT2A
SCHEMBL30123663 0.85 ANPEP (0.60) DPP4ANPEPCRHBPCRHR2KMT2A
SCHEMBL29382416 0.85 DPP4 (0.61) DPP4ANPEPCRHBPCRHR2NR1H3
SCHEMBL11600942 0.84 DPP4 (0.55) DPP4ANPEPCRHBPCRHR2NR1H3
SCHEMBL11600949 0.84 DPP4 (0.55) DPP4ANPEPCRHBPCRHR2NR1H3
SCHEMBL11018579 0.83 DPP4 (0.70) DPP4ANPEPCRHBPCRHR2KMT2A
SCHEMBL11018633 0.83 DPP4 (0.70) DPP4ANPEPCRHBPCRHR2
SCHEMBL987786 0.83 ANPEP (0.70) DPP4ANPEPCRHBPCRHR2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250113829-A1 HIGH MOLECULAR WEIGHT MODIFIED RNA COMPOSITIONS nanoSUR LLC 2025-04-10 — — US disclosed
CN-117466799-B N-substituted phthalic acid diamide preparation method of imine compound 西北师范大学 2024-12-24 — — CN disclosed
EP-4396348-A2 HIGH MOLECULAR WEIGHT MODIFIED DSRNA COMPOSITIONS Nanosur LLC (US) 2024-07-10 — — EP disclosed
CN-118302524-A High molecular weight modified dsRNA compositions 纳诺索尔公司 2024-07-05 — — CN disclosed
CN-117466799-A Preparation method of N-substituted phthalimide compound 西北师范大学 2024-01-30 — — CN disclosed
WO-2023034849-A2 HIGH MOLECULAR WEIGHT MODIFIED dsRNA COMPOSITIONS nanoSUR LLC (US) 2023-03-09 — — WO disclosed
US-11174480-B2 Post-transcriptionally chemically modified double strand RNAs nanoSUR LLC (US) 2021-11-16 — — US disclosed
CN-108291055-B Sulfur-containing compounds as solvents 诺华丝国际股份有限公司 2021-07-06 — — CN disclosed
CN-112707851-A Sulfur-containing compounds as solvents 诺华丝国际股份有限公司 2021-04-27 — — CN disclosed
US-10640769-B2 Post-transcriptionally chemically modified double strand RNAs nanoSUR LLC (US) 2020-05-05 — — US disclosed
EP-0245989-B1 FLUOROPHTHALIMIDES MEIJI SEIKA KABUSHIKI KAISHA (JP) 1991-07-10 — — EP disclosed
US-4839378-A FOR CONTROLLING PLANT DISEASES MEIJI SEIKA KABUSHIKI KAISHA (JP) 1989-06-13 — — US disclosed
EP-0306222-A2 Benzenesulfonanilide derivatives and fungicides for agriculture and horticulture HOKKO CHEMICAL INDUSTRY CO., LTD (JP) 1989-03-08 — — EP disclosed
EP-0245989-A2 Fluorophthalimides MEIJI SEIKA KABUSHIKI KAISHA (JP) 1987-11-19 — — EP disclosed
US-4420486-A Benzoxazolone derivatives, processes for preparation thereof and compositions containing them HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 1983-12-13 — — US disclosed
US-4391804-A Imidazole derivatives and fungicidal composition containing the same HOKKO CHEMICAL INDUSTRY COMPANY, LTD. (JP) 1983-07-05 — — US disclosed
US-4304778-A 4-Aminoquinazoline derivatives having fungicidal, anti-insect and acaricidal properties SANKYO COMPANY LIMITED (JP) 1981-12-08 — — US disclosed
US-4279908-A Pyridazine derivatives and their use as agricultural fungicides SANKYO COMPANY LIMITED (JP) 1981-07-21 — — US disclosed
US-4052395-A AGRICULTURAL FUNGICIDAL COMPOSITIONS CONTAINING 6-(SUBSTITUTED PHENYL)-PYRIDAZINONES AND SAID PYRIDAZINONES SANKYO COMPANY LIMITED (JA) 1977-10-04 — — US disclosed
US-4036631-A Pyrazolone derivatives and their use as herbicides SANKYO COMPANY LIMITED (JA) 1977-07-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250113829-A1 HIGH MOLECULAR WEIGHT MODIFIED RNA COMPOSITIONS NSUN2, NSUN3, RNGTT DPP4 3240/4885ANPEP 2082/4885CRHBP 1276/4885
US-11174480-B2 Post-transcriptionally chemically modified double strand RNAs NSUN2, NSUN3, RNGTT DPP4 4394/4885ANPEP 3641/4885CRHBP 1562/4885
US-10640769-B2 Post-transcriptionally chemically modified double strand RNAs NSUN2, NSUN3, RNGTT DPP4 4394/4885ANPEP 3641/4885CRHBP 1562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.