Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PTPRC | P08575 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14922781 | 0.89 | MAPT (0.54) | HSP90AA1MAPTCDK5CDK5R1NCOA1 | |
| SCHEMBL12111782 | 0.82 | HSP90AA1 (0.53) | HSP90AA1MAPTCDK5CDK5R1NCOA1 | |
| SCHEMBL11786497 | 0.77 | MAPT (0.68) | HSP90AA1MAPTCDK5CDK5R1NCOA1 | |
| SCHEMBL11786504 | 0.77 | MAPT (0.68) | HSP90AA1MAPTCDK5CDK5R1NCOA1 | |
| SCHEMBL16601719 | 0.76 | MAPT (0.46) | HSP90AA1MAPTCDK5CDK5R1NCOA1 | |
| SCHEMBL4402246 | 0.73 | ALDH1A1 (0.50) | HSP90AA1MAPTTDP1KMT2AMEN1 | |
| SCHEMBL11781110 | 0.73 | MAPT (0.62) | HSP90AA1MAPTCDK5CDK5R1NCOA1 | |
| SCHEMBL11782222 | 0.72 | MAPT (0.61) | HSP90AA1MAPTCDK5CDK5R1NCOA1 | |
| SCHEMBL11781591 | 0.72 | MAPT (0.61) | HSP90AA1MAPTCDK5CDK5R1NCOA1 | |
| SCHEMBL11781585 | 0.72 | MAPT (0.61) | HSP90AA1MAPTCDK5CDK5R1NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |