SCHEMBL16601710

SCHEMBL16601710

O=C1C(=O)c2ccc(-c3ccc(O)cc3)cc2-c2ccccc21

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.75
KMT2A Q03164 4/20 0.75
NPC1 O15118 3/20 0.75
MAPT P10636 3/20 0.75
RAB9A P51151 3/20 0.75
SMN1; SMN2 Q16637 3/20 0.75
APAF1 O14727 2/20 0.75
LMNA P02545 2/20 0.75
THRB P10828 2/20 0.75
HTT P42858 2/20 0.75
GALK1 P51570 2/20 0.75
BLM P54132 2/20 0.75
NPSR1 Q6W5P4 2/20 0.75
XBP1 P17861 1/20 0.75
PTBP1 P26599 1/20 0.75
SMAD3 P84022 1/20 0.75
ATM Q13315 1/20 0.75
L3MBTL1 Q9Y468 1/20 0.75
PTPRC P08575 8/20 0.53
PTPN1 P18031 3/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16601659 0.96 MEN1 (0.69) MEN1KMT2ANPC1MAPTRAB9A
SCHEMBL28914940 0.92 MEN1 (0.63) MEN1KMT2ANPC1MAPTRAB9A
SCHEMBL12112513 0.92 MEN1 (0.61) MEN1KMT2ANPC1MAPTRAB9A
SCHEMBL10936171 0.90 MEN1 (0.60) MEN1KMT2ANPC1MAPTRAB9A
SCHEMBL16601661 0.88 MEN1 (0.55) MEN1KMT2ANPC1MAPTRAB9A
SCHEMBL15383587 0.86 MEN1 (1.00) MEN1KMT2ANPC1MAPTRAB9A
SCHEMBL12553057 0.86 MEN1 (0.83) MEN1KMT2ANPC1MAPTRAB9A
SCHEMBL12553052 0.86 MEN1 (0.83) MEN1KMT2ANPC1MAPTRAB9A
SCHEMBL12553042 0.86 MEN1 (0.83) MEN1KMT2ANPC1MAPTRAB9A
SCHEMBL8210089 0.84 ESR1 (0.67) MEN1KMT2ANPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed