SCHEMBL16601769

SCHEMBL16601769

CCCCCCN1C(=O)c2ccc3c4ccc5c6c(ccc(c7ccc(c2c37)C1=O)c64)C(=O)N(C(CC)CO)C5=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 1/20 0.49
HIF1A Q16665 1/20 0.49
MEN1 O00255 2/20 0.49
RGS12 O14924 2/20 0.49
HTT P42858 2/20 0.49
KMT2A Q03164 2/20 0.49
KDM4E B2RXH2 1/20 0.49
NPC1 O15118 1/20 0.49
ALDH1A1 P00352 1/20 0.49
LMNA P02545 1/20 0.49
PABPC1 P11940 1/20 0.49
RECQL P46063 1/20 0.49
RAB9A P51151 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
TERT O14746 6/20 0.45
USP2 O75604 1/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 1/20 0.40
MAPK1 P28482 1/20 0.40
ATM Q13315 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16601806 0.90 KDM4E (0.55) STAT3HIF1AMEN1RGS12HTT
SCHEMBL17718733 0.86 KDM4E (0.64) STAT3HIF1AMEN1RGS12HTT
SCHEMBL7485629 0.86 STAT3 (0.52) STAT3HIF1AMEN1RGS12HTT
SCHEMBL16601834 0.86 TERT (0.43) STAT3HIF1AMEN1RGS12HTT
SCHEMBL16601709 0.85 KDM4E (0.60) STAT3HIF1AMEN1RGS12HTT
SCHEMBL418871 0.84 STAT3 (0.65) STAT3HIF1AMEN1RGS12HTT
SCHEMBL18376159 0.84 STAT3 (0.65) STAT3HIF1AMEN1RGS12HTT
SCHEMBL8071104 0.84 STAT3 (0.65) STAT3HIF1AMEN1RGS12HTT
SCHEMBL7485132 0.84 STAT3 (0.65) STAT3HIF1AMEN1RGS12HTT
SCHEMBL1105114 0.84 STAT3 (0.65) STAT3HIF1AMEN1RGS12HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed