SCHEMBL16601784

SCHEMBL16601784

N#CC(C#N)=C1c2cc(-c3ccc(CO)cc3)ccc2-c2ccc(-c3ccc(CO)cc3)cc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.44
PKM P14618 2/20 0.44
ALDH1A1 P00352 1/20 0.44
GAA P10253 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
PDK2 Q15119 1/20 0.41
KIF11 P52732 1/20 0.38
PDCD1 Q15116 1/20 0.37
CD274 Q9NZQ7 1/20 0.37
MKNK1 Q9BUB5 1/20 0.34
MKNK2 Q9HBH9 1/20 0.34
CHEK1 O14757 2/20 0.34
HPRT1 P00492 1/20 0.34
FYN P06241 2/20 0.33
ERN1 O75460 1/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
MMP3 P08254 1/20 0.32
KDM1A O60341 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16602040 0.94 PDK2 (0.47) MAPTPKMALDH1A1GAAMEN1
SCHEMBL15765913 0.83 MAPT (0.38) MAPTPKMALDH1A1GAAMEN1
SCHEMBL10075457 0.79 MMP3 (0.47) MAPTPKMALDH1A1GAAMEN1
SCHEMBL10075613 0.79 MAPT (0.46) MAPTPKMALDH1A1GAAMEN1
SCHEMBL14234413 0.78 MAPT (0.45) MAPTPKMALDH1A1GAAMEN1
SCHEMBL12117589 0.78 MAPT (0.49) MAPTPKMALDH1A1GAAMEN1
SCHEMBL12148976 0.77 MAPT (0.44) MAPTPKMALDH1A1GAAMEN1
SCHEMBL12118010 0.77 MAPT (0.44) MAPTPKMALDH1A1GAAMEN1
SCHEMBL12117577 0.77 MMP3 (0.44) MAPTPKMALDH1A1GAAMEN1
SCHEMBL16601968 0.76 MAPT (0.36) MAPTPKMALDH1A1GAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed