SCHEMBL16601791

SCHEMBL16601791

O=C1C=C/C(=C2/C=CC(=O)C(c3ccc(O)cc3)=C2)C=C1c1ccc(O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 4/20 0.50
PTPN1 P18031 1/20 0.50
MGAM O43451 1/20 0.47
GAA P10253 1/20 0.47
SI P14410 1/20 0.47
MGAM2 Q2M2H8 1/20 0.47
HSD17B3 P37058 1/20 0.47
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
KDM4E B2RXH2 3/20 0.44
MAPT P10636 3/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
PKM P14618 1/20 0.44
MAPK1 P28482 1/20 0.44
MCL1 Q07820 1/20 0.44
SETD7 Q8WTS6 2/20 0.42
ESR1 P03372 3/20 0.40
ESR2 Q92731 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16601731 0.93 HSD17B3 (0.50) BACE1PTPN1MGAMGAASI
SCHEMBL10765128 0.85 HSD17B3 (0.64) BACE1PTPN1MGAMGAASI
SCHEMBL17208872 0.79 KDM4E (0.40) BACE1PTPN1MGAMGAASI
SCHEMBL28864094 0.79 HSD17B3 (0.56) BACE1PTPN1MGAMGAASI
SCHEMBL21887168 0.78 MAOA (0.72) BACE1PTPN1GAAHSD17B3MAOA
SCHEMBL16601790 0.75 BACE1 (0.43) BACE1PTPN1MGAMGAASI
SCHEMBL16601789 0.73 HSD17B3 (0.46) GAAHSD17B3MAOAMAOBKDM4E
SCHEMBL16656179 0.73 MAPT (0.43) BACE1HSD17B3MAOAMAOBKDM4E
SCHEMBL28352043 0.72 MGAM (0.44) BACE1PTPN1MGAMGAASI
SCHEMBL27169536 0.72 HSD17B3 (0.78) BACE1PTPN1HSD17B3MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed