Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.47 |
| ▸ | CCND1 | P24385 | 1/20 | 0.47 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14198007 | 0.84 | LCK (0.54) | LCKKDM4EABL1BCRCCNB2 | |
| SCHEMBL1137220 | 0.80 | AKR1C3 (0.66) | LCKKDM4EABL1BCRCCNB2 | |
| SCHEMBL1137218 | 0.80 | AKR1C3 (0.66) | LCKKDM4EABL1BCRCCNB2 | |
| SCHEMBL1682626 | 0.79 | ABL1 (0.49) | LCKKDM4EABL1BCRCCNB2 | |
| SCHEMBL8040509 | 0.78 | KDM4E (0.60) | LCKKDM4ECCNB2CDK1CDK4 | |
| Phenol SCHEMBL11889591 | 0.77 | AKR1C3 (0.67) | LCKKDM4ECCNB2CDK1CDK4 | |
| SCHEMBL31634782 | 0.77 | KDM4E (0.55) | LCKKDM4ECCNB2CDK1CDK4 | |
| SCHEMBL30938425 | 0.77 | KDM4E (0.55) | LCKKDM4ECCNB2CDK1CDK4 | |
| SCHEMBL7551989 | 0.77 | KDM4E (0.55) | LCKKDM4ECCNB2CDK1CDK4 | |
| SCHEMBL3686105 | 0.77 | LCK (0.56) | LCKKDM4EABL1BCRCCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993762-B2 | Total synthesis of thaxtomin A analogues and their intermediates | MARRONE BIO INNOVATIONS, INC. (US) | 2015-03-31 | — | — | US | disclosed |