Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.45 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.45 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1137218 | 0.96 | AKR1C3 (0.66) | AKR1C3KDM4EMMP1MMP2MMP9 | |
| SCHEMBL1137220 | 0.96 | AKR1C3 (0.66) | AKR1C3KDM4EMMP1MMP2MMP9 | |
| SCHEMBL8746676 | 0.85 | AKR1C3 (0.76) | AKR1C3KDM4ESLC9A1SLC9A3SLC9A2 | |
| SCHEMBL8746678 | 0.85 | AKR1C3 (0.76) | AKR1C3KDM4ESLC9A1SLC9A3SLC9A2 | |
| SCHEMBL3095394 | 0.82 | AKR1C3 (0.71) | AKR1C3SLC9A1SLC9A3SLC9A2TBXAS1 | |
| SCHEMBL41906 | 0.81 | AKR1C3 (1.00) | AKR1C3TBXAS1MEN1ALDH1A1KMT2A | |
| SCHEMBL16568719 | 0.81 | AKR1C3 (1.00) | AKR1C3TBXAS1MEN1ALDH1A1KMT2A | |
| SCHEMBL37034 | 0.81 | AKR1C3 (1.00) | AKR1C3TBXAS1MEN1ALDH1A1KMT2A | |
| SCHEMBL581982 | 0.81 | AKR1C3 (1.00) | AKR1C3TBXAS1MEN1ALDH1A1KMT2A | |
| SCHEMBL8462385 | 0.81 | SLC9A1 (0.54) | AKR1C3KDM4ESLC9A1SLC9A3SLC9A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782599-A1 | DENTAL POLYMERIZABLE COMPOSITION BASED ON CONDENSED SILANES | VOCO GmbH (DE) | 2021-02-24 | — | — | EP | claimed |
| EP-2623087-B1 | Dental composite materials containing tricyclic plasticisers | VOCO GMBH (DE) | 2019-07-17 | — | — | EP | claimed |
| EP-2623086-B1 | Curable mixture comprising plasticisers with a polyalicyclic structure element for use in the production of dental materials. | VOCO GMBH (DE) | 2019-07-10 | — | — | EP | claimed |
| EP-2623086-A2 | Curable mixture comprising plasticisers with a polyalicyclic structure element for use in the production of dental materials. | VOCO GmbH (DE) | 2013-08-07 | — | — | EP | claimed |
| EP-2623087-A2 | Dental composite materials containing tricyclic plasticisers | VOCO GmbH (DE) | 2013-08-07 | — | — | EP | claimed |
| EP-3782599-A1 | DENTAL POLYMERIZABLE COMPOSITION BASED ON CONDENSED SILANES | VOCO GmbH (DE) | 2021-02-24 | — | — | EP | disclosed |
| EP-3520765-B1 | RADICALLY CURABLE DENTAL COMPOSITIONS | VOCO GMBH (DE) | 2020-07-15 | — | — | EP | disclosed |
| EP-3520765-A1 | RADICALLY CURABLE DENTAL COMPOSITIONS | VOCO GmbH (DE) | 2019-08-07 | — | — | EP | disclosed |
| EP-2623087-B1 | Dental composite materials containing tricyclic plasticisers | VOCO GMBH (DE) | 2019-07-17 | — | — | EP | disclosed |
| EP-2623086-B1 | Curable mixture comprising plasticisers with a polyalicyclic structure element for use in the production of dental materials. | VOCO GMBH (DE) | 2019-07-10 | — | — | EP | disclosed |
| EP-3020361-B1 | USE OF RADICALLY HARDENING COMPOSITIONS IN GENERATIVE PRODUCTION METHODS | VOCO GMBH (DE) | 2019-05-15 | — | — | EP | disclosed |
| EP-3020360-B1 | RADICALLY CURABLE DENTAL COMPOSITIONS | VOCO GMBH (DE) | 2019-05-08 | — | — | EP | disclosed |
| EP-2481391-B1 | Dental provisional superstructures and materials for producing same and corresponding method | VOCO GMBH (DE) | 2017-07-05 | — | — | EP | disclosed |
| US-9421152-B2 | Dental temporary superstructures and materials for production thereof and corresponding methods | VOCO GMBH (DE) | 2016-08-23 | — | — | US | disclosed |
| EP-3020360-A1 | RADICALLY CURABLE DENTAL COMPOSITIONS | VOCO GmbH (DE) | 2016-05-18 | — | — | EP | disclosed |
| EP-3020361-A1 | USE OF RADICALLY HARDENING COMPOSITIONS IN GENERATIVE PRODUCTION METHODS | VOCO GmbH (DE) | 2016-05-18 | — | — | EP | disclosed |
| EP-2623086-A2 | Curable mixture comprising plasticisers with a polyalicyclic structure element for use in the production of dental materials. | VOCO GmbH (DE) | 2013-08-07 | — | — | EP | disclosed |
| EP-2623087-A2 | Dental composite materials containing tricyclic plasticisers | VOCO GmbH (DE) | 2013-08-07 | — | — | EP | disclosed |
| US-20120196249-A1 | DENTAL TEMPORARY SUPERSTRUCTURES AND MATERIALS FOR PRODUCTION THEREOF AND CORRESPONDING METHODS | VOCO GMBH (DE) | 2012-08-02 | — | — | US | disclosed |
| EP-2481391-A2 | Dental provisional superstructures and materials for producing same and corresponding method | VOCO GmbH (DE) | 2012-08-01 | — | — | EP | disclosed |