Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9971822 | 0.78 | ESR2 (0.32) | ESR2 | |
| SCHEMBL9971812 | 0.78 | ESR2 (0.32) | ESR2 | |
| SCHEMBL13841014 | 0.77 | ESR2 (0.32) | ESR2 | |
| SCHEMBL14317174 | 0.74 | — | — | |
| SCHEMBL15997685 | 0.74 | — | — | |
| SCHEMBL12710440 | 0.74 | — | — | |
| SCHEMBL14153745 | 0.70 | ESR2 (0.32) | ESR2 | |
| SCHEMBL8444703 | 0.69 | — | — | |
| SCHEMBL14731527 | 0.69 | — | — | |
| SCHEMBL9973233 | 0.69 | ESR2 (0.38) | ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2721004-B1 | 3-DESOXY-2-METHYLENE-19-NOR-VITAMIN D ANALOGS AND THEIR USES | WISCONSIN ALUMNI RES FOUND (US) | 2017-07-26 | — | — | EP | disclosed |
| US-8993547-B2 | 3-desoxy-2-methylene-19-nor-vitamin D analogs and their uses | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2015-03-31 | — | — | US | disclosed |