Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9971812 | 1.00 | ESR2 (0.32) | ESR2 | |
| SCHEMBL16602152 | 0.78 | ESR2 (0.33) | ESR2 | |
| SCHEMBL13804818 | 0.78 | ESR2 (0.31) | ESR2 | |
| SCHEMBL14317174 | 0.77 | — | — | |
| SCHEMBL12710440 | 0.73 | — | — | |
| SCHEMBL1604234 | 0.72 | STAT3 (0.35) | — | |
| SCHEMBL14401987 | 0.70 | — | — | |
| SCHEMBL8444703 | 0.68 | — | — | |
| SCHEMBL13993773 | 0.68 | ESR2 (0.30) | ESR2 | |
| SCHEMBL9973233 | 0.68 | ESR2 (0.38) | ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993547-B2 | 3-desoxy-2-methylene-19-nor-vitamin D analogs and their uses | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2015-03-31 | — | — | US | disclosed |
| US-8642579-B2 | 1-desoxy-2-methylene-19-nor-vitamin D analogs and their uses | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-02-04 | — | — | US | disclosed |
| US-8518917-B2 | 2-methylene-19-nor-vitamin D analogs and their uses | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-08-27 | — | — | US | disclosed |
| US-20120322775-A1 | 3-Desoxy-2-Methylene-19-Nor-Vitamin D Analogs and Their Uses | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-12-20 | — | — | US | disclosed |
| US-20120157418-A1 | 2-Methylene-19-Nor-Vitamin D Analogs and Their Uses | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-06-21 | — | — | US | disclosed |
| US-20110082121-A1 | 1-Desoxy-2-Methylene-19-Nor-Vitamin D Analogs and Their Uses | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2011-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110082121-A1 | 1-Desoxy-2-Methylene-19-Nor-Vitamin D Analogs and Their Uses | VDR, CYP24A1, CYP2R1 | ESR2 626/4885 |
| US-20120157418-A1 | 2-Methylene-19-Nor-Vitamin D Analogs and Their Uses | CYP24A1, CYP2R1, CYP27B1 | ESR2 734/4885 |
| US-20120322775-A1 | 3-Desoxy-2-Methylene-19-Nor-Vitamin D Analogs and Their Uses | VDR, CYP24A1, CYP2R1 | ESR2 355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.