Terephthalic Acid

Terephthalic Acid

SCHEMBL166041

O=C([O-])c1ccc(C(=O)[O-])cc1.[Ba+2]

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1

The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA2 P00918 18/20 0.68
CA1 P00915 17/20 0.68
CA4 P22748 1/20 0.63
TP53 P04637 1/20 0.44
TSHR P16473 1/20 0.44
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL8610484 0.97 CA2 (0.65) CA2CA1CA4TP53TSHR
Terephthalic Acid SCHEMBL1006722 0.93 CA2 (0.68) CA2CA1CA4TP53TSHR
Terephthalic Acid SCHEMBL21958268 0.93 CA2 (0.68) CA2CA1CA4TP53TSHR
Terephthalic Acid SCHEMBL1151275 0.93 CA2 (0.68) CA2CA1CA4TP53TSHR
Terephthalic Acid SCHEMBL6665082 0.93 CA2 (0.68) CA2CA1CA4TP53TSHR
Terephthalic Acid SCHEMBL1535442 0.93 CA2 (0.68) CA2CA1CA4TP53TSHR
Terephthalic Acid SCHEMBL2841686 0.93 CA2 (0.78) CA2CA1CA4TP53TSHR
Terephthalic Acid SCHEMBL10900872 0.93 CA2 (0.68) CA2CA1CA4TP53TSHR
Terephthalic Acid SCHEMBL20704875 0.93 CA2 (0.68) CA2CA1CA4TP53TSHR
Terephthalic Acid SCHEMBL5969820 0.93 CA2 (0.68) CA2CA1CA4TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113789039-B Biodegradable polyester heat shrinkable film and preparation method thereof 江苏景宏新材料科技有限公司 2022-06-14 CN claimed
CN-113789039-A Biodegradable polyester heat shrinkable film and preparation method thereof 江苏景宏新材料科技有限公司 2021-12-14 CN claimed
CN-111333973-B Anti-aging laminating film 江苏金材科技有限公司 2021-09-10 CN claimed
CN-111333973-A Anti-aging laminating film 江苏金材科技有限公司 2020-06-26 CN claimed
CN-110684246-A Tread rubber of low-saturation pattern oil-resistant tire and preparation method thereof 徐州徐轮橡胶有限公司 2020-01-14 CN claimed
EP-0478199-B1 Polyvinyl chloride resin composition for powder molding SUMITOMO CHEMICAL CO (JP) 1997-06-25 EP claimed
EP-0478199-A2 Polyvinyl chloride resin composition for powder molding SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-04-01 EP claimed
US-4861816-A Polyvinyl chloride resin composition for powder molding SUMITOMO CHEMICAL COMPANY (JP) 1989-08-29 US claimed
US-4198458-A MAGNETIC TAPES TEIJIN LIMITED (JP) 1980-04-15 US claimed
CN-110366597-B Blood profiling with protease inhibitors 善威生物私人有限公司 2024-03-29 CN disclosed
US-20240060997-A1 Blood Preparation and Profiling SANGUI BIO PTY LTD (AU) 2024-02-22 US disclosed
CN-114736491-B Degradable heat-shrinkable film, degradable heat-shrinkable multilayer film and preparation method thereof 江苏景宏新材料科技有限公司 2023-10-13 CN disclosed
US-11693006-B2 Blood profiling with protease inhibitors SANGUI BIO PTY. LTD (AU) 2023-07-04 US disclosed
CN-114736491-A Degradable heat shrinkable film, degradable heat shrinkable multilayer film and preparation method thereof 江苏景宏新材料科技有限公司 2022-07-12 CN disclosed
EP-0501543-A1 Process for the production of polyesters with increased electroconductivity AGFA-GEVAERT N.V. (BE) 1992-09-02 EP disclosed
EP-0501545-A1 Process for the production of polyesters with enhanced thermo-oxidative stability AGFA-GEVAERT N.V. (BE) 1992-09-02 EP disclosed
EP-0478199-A2 Polyvinyl chloride resin composition for powder molding SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-04-01 EP disclosed
EP-0403664-A1 AROMATIC POLYESTER FILM AND PRODUCTION THEREOF TEIJIN LIMITED (JP) 1990-12-27 EP disclosed
US-4952634-A Curable carboxylated polymers containing polymeric polyvalent metal salt crosslinking agents SYNTHETIC PRODUCTS COMPANY (US) 1990-08-28 US disclosed
US-4861816-A Polyvinyl chloride resin composition for powder molding SUMITOMO CHEMICAL COMPANY (JP) 1989-08-29 US disclosed