Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 6/20 | 0.61 |
| ▸ | F11 | P03951 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18100239 | 0.93 | F11 (0.59) | PLGF11KMT2AATMMEN1 | |
| SCHEMBL16604402 | 0.92 | F11 (0.57) | PLGF11KMT2AATMMEN1 | |
| SCHEMBL16604374 | 0.92 | PLG (0.58) | PLGF11KMT2AATMMEN1 | |
| SCHEMBL16609151 | 0.90 | F11 (0.62) | PLGF11KMT2AATMMEN1 | |
| SCHEMBL18020926 | 0.90 | F11 (0.63) | PLGF11KMT2AATMMEN1 | |
| SCHEMBL16604376 | 0.89 | PLG (0.66) | PLGF11KMT2AATMMEN1 | |
| SCHEMBL17986484 | 0.89 | F11 (0.63) | PLGF11KMT2AATMMEN1 | |
| SCHEMBL16609132 | 0.89 | F11 (0.63) | PLGF11KMT2AATMMEN1 | |
| SCHEMBL16604396 | 0.89 | F11 (0.61) | PLGF11KMT2AATMMEN1 | |
| SCHEMBL16607035 | 0.89 | PLG (0.70) | PLGF11KMT2AATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015044172-A1 | SUBSTITUTED PHENYLALANINE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-04-02 | — | — | WO | disclosed |