Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.70 |
| ▸ | ATM | Q13315 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | ACACA | Q13085 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25964562 | 1.00 | KMT2A (0.70) | KMT2AATMMEN1MAPK1LMNA | |
| SCHEMBL388984 | 0.92 | KMT2A (0.82) | KMT2AATMMEN1MAPK1LMNA | |
| SCHEMBL28057007 | 0.92 | KMT2A (0.82) | KMT2AATMMEN1MAPK1LMNA | |
| SCHEMBL388983 | 0.92 | KMT2A (0.82) | KMT2AATMMEN1MAPK1LMNA | |
| SCHEMBL16609114 | 0.91 | KMT2A (0.69) | KMT2AATMMEN1MAPK1LMNA | |
| SCHEMBL17982949 | 0.91 | KMT2A (0.69) | KMT2AATMMEN1MAPK1LMNA | |
| SCHEMBL16604445 | 0.91 | KMT2A (0.69) | KMT2AATMMEN1MAPK1LMNA | |
| SCHEMBL18093140 | 0.91 | KMT2A (0.69) | KMT2AATMMEN1MAPK1LMNA | |
| SCHEMBL17961971 | 0.91 | KMT2A (0.69) | KMT2AATMMEN1MAPK1LMNA | |
| SCHEMBL16604349 | 0.91 | KMT2A (0.69) | KMT2AATMMEN1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015044172-A1 | SUBSTITUTED PHENYLALANINE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-04-02 | — | — | WO | disclosed |
| WO-2015044169-A1 | SUBSTITUTED PHENYLALANINE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-04-02 | — | — | WO | disclosed |
| WO-2015044163-A1 | SUBSTITUTED PHENYLALANINE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-04-02 | — | — | WO | disclosed |